US 12,174,162 B2
Hazardous substance analyzing system
Tetsuo Tanigawa, Kyoto (JP); Natsuyo Asano, Kyoto (JP); Zhao Qi Zhan, Singapore (SG); Yin Ling Chew, Singapore (SG); Jun Xiang Lee, Singapore (SG); and Jie Xing, Singapore (SG)
Assigned to SHIMADZU CORPORATION, Kyoto (JP)
Appl. No. 17/295,643
Filed by SHIMADZU CORPORATION, Kyoto (JP)
PCT Filed Oct. 30, 2019, PCT No. PCT/JP2019/042672
§ 371(c)(1), (2) Date May 20, 2021,
PCT Pub. No. WO2020/110583, PCT Pub. Date Jun. 4, 2020.
Claims priority of application No. 10201810706P (SG), filed on Nov. 29, 2018.
Prior Publication US 2022/0003727 A1, Jan. 6, 2022
Int. Cl. G01N 30/72 (2006.01); G01N 30/02 (2006.01); G01N 30/86 (2006.01); G01N 30/88 (2006.01); H01J 49/42 (2006.01)
CPC G01N 30/7266 (2013.01) [G01N 30/86 (2013.01); G01N 30/88 (2013.01); H01J 49/42 (2013.01); G01N 2030/027 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A hazardous substance analyzing system for quantitatively analyzing hazardous substances contained in a sample by using an analyzing device, wherein:
a liquid chromatograph mass spectrometer is used as the analyzing device, the liquid chromatograph mass spectrometer including a liquid chromatograph for temporally separating substances contained in a sample to be analyzed and a tandem mass spectrometer for ionizing the substances in the sample temporally separated by the liquid chromatograph and detecting product ions generated by dissociating a specific kind of ion among ions produced by ionization; and
the hazardous substance analyzing system includes:
a) an information storage section in which control information for performing an analysis according to two or more measurement methods is stored, the control information including at least a gradient condition related to a plurality of mobile phases in the liquid chromatograph as well as a retention time and a multiple reaction monitoring (MRM) transition for detecting each substance in the tandem mass spectrometer, and the two or more measurement methods selected from following six measurement methods:
a1) a first measurement method for detecting, by a single analysis, a plurality of specific substances which are primary aromatic amines;
a2) a second measurement method for detecting, by a single analysis, a plurality of specific substances which are first azo compounds, under a condition that a first mobile phase is used as one of the mobile phases in the liquid chromatograph;
a3) a third measurement method for detecting, by a single analysis, a plurality of specific substances which are second azo compounds under a condition that a second mobile phase different from the first mobile phase is used as one of the mobile phases in the liquid chromatograph, the second azo compounds being different than the first azo compounds;
a4) a fourth analysis method for detecting, by a single analysis, a plurality of specific substances which are perfluorocompounds;
a5) a fifth analysis method for detecting, by a single analysis, a plurality of specific substances which are alkylphenol ethoxylates; and
a6) a sixth measurement method for detecting, by a single analysis, a plurality of specific substances which are alkylphenols;
b) a method selection assistant for displaying identifiers of the two or more measurement methods stored in the information storage section on a screen of a display unit and allowing a user to select one measurement method from the two or more measurement methods; and
c) an analysis controller for reading, from the information storage section, the control information for the measurement method selected by a user with the method selection assistant, and controlling an operation of the liquid chromatograph and an operation of the tandem mass spectrometer according to the read control information.