US 12,174,120 B2
Image acquisition device, image acquisition method, and spatial light modulation unit
Yuu Takiguchi, Hamamatsu (JP)
Assigned to HAMAMATSU PHOTONICS K.K., Hamamatsu (JP)
Appl. No. 15/772,844
Filed by HAMAMATSU PHOTONICS K.K., Hamamatsu (JP)
PCT Filed Sep. 20, 2016, PCT No. PCT/JP2016/077687
§ 371(c)(1), (2) Date May 2, 2018,
PCT Pub. No. WO2017/077776, PCT Pub. Date May 11, 2017.
Claims priority of application No. 2015-218528 (JP), filed on Nov. 6, 2015.
Prior Publication US 2018/0313759 A1, Nov. 1, 2018
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 21/64 (2006.01); G01N 21/01 (2006.01); G02B 21/06 (2006.01); G02B 21/36 (2006.01); G02B 21/16 (2006.01); G02B 26/06 (2006.01)
CPC G01N 21/6458 (2013.01) [G01N 21/01 (2013.01); G01N 21/64 (2013.01); G02B 21/06 (2013.01); G02B 21/361 (2013.01); G02B 21/365 (2013.01); G01N 2201/0635 (2013.01); G02B 21/16 (2013.01); G02B 21/367 (2013.01); G02B 26/06 (2013.01)] 10 Claims
OG exemplary drawing
 
1. An image acquisition device for acquiring an image of an observation target by radiating structured illumination light, the image acquisition device comprising:
a light source configured to output light;
a spatial light modulator having a plurality of pixels two-dimensionally arranged and configured to modulate a phase of the light output from the light source for each of the plurality of pixels;
an objective lens configured to radiate the modulated light to the observation target;
a photodetector configured to capture an image of the light from the observation target; and
a controller configured to control an amount of phase modulation for each of the plurality of pixels in accordance with a phase pattern in which phase values corresponding to the plurality of pixels are two-dimensionally distributed, the phase pattern generated based on a predetermined basic phase pattern including a first region in which the phase value continuously increases in a predetermined direction and a second region in which the phase value continuously decreases in the predetermined direction and facing the first region in the predetermined direction,
wherein in both the first region and the second region in the basic pattern, the phase value is constant in a direction orthogonal to the predetermined direction,
wherein the basic phase pattern is non-axisymmetric with respect to a straight line passing through a center in the predetermined direction and orthogonal to the predetermined direction,
wherein the phase value is continuous at a boundary between the first region and the second region,
wherein an absolute value of a gradient of the phase value in the second region is larger than an absolute value of a gradient of the phase value in the first region, and
wherein an amount of phase delay of light modulated by the second region is larger than an amount of phase delay of light modulated by the first region based on the phase value being continuous at the boundary between the first region and the second region and based on the absolute value of the gradient of the phase value in the second region being larger than the absolute value of the gradient of the phase value in the first region.