US 12,173,310 B2
Hypothermic 3D bioprinting of living tissues supported by perfusable vasculature
Jordan Miller, Houston, TX (US); Anderson Ta, Houston, TX (US); and Bagrat Grigoryan, Spring, TX (US)
Assigned to WILLIAM MARSH RICE UNIVERSITY, Houston, TX (US)
Filed by WILLIAM MARSH RICE UNIVERSITY, Houston, TX (US)
Filed on Jul. 3, 2023, as Appl. No. 18/217,805.
Application 17/071,923 is a division of application No. 15/709,392, filed on Sep. 19, 2017, granted, now 10,844,350, issued on Nov. 24, 2020.
Application 18/217,805 is a continuation of application No. 17/849,904, filed on Jun. 27, 2022.
Application 17/849,904 is a continuation of application No. 17/071,923, filed on Oct. 15, 2020, granted, now 11,371,014, issued on Jun. 26, 2022.
Application 15/709,392 is a continuation of application No. PCT/US2016/023302, filed on Mar. 18, 2016.
Claims priority of provisional application 62/136,004, filed on Mar. 20, 2015.
Prior Publication US 2023/0348848 A1, Nov. 2, 2023
Int. Cl. C08F 2/46 (2006.01); B29C 64/129 (2017.01); B29C 64/393 (2017.01); B33Y 10/00 (2015.01); B33Y 50/02 (2015.01); B33Y 70/00 (2020.01); C08F 2/50 (2006.01); C08G 61/04 (2006.01); C12M 1/12 (2006.01); C12M 3/00 (2006.01); C12N 5/00 (2006.01); C12N 5/078 (2010.01); B29K 71/00 (2006.01)
CPC C12N 5/0062 (2013.01) [B29C 64/129 (2017.08); B29C 64/393 (2017.08); B33Y 10/00 (2014.12); B33Y 50/02 (2014.12); B33Y 70/00 (2014.12); C12M 3/00 (2013.01); C12M 21/08 (2013.01); C12M 25/14 (2013.01); C12N 5/0068 (2013.01); C12N 5/0641 (2013.01); B29K 2071/02 (2013.01); C12N 2513/00 (2013.01); C12N 2533/30 (2013.01); C12N 2537/00 (2013.01)] 20 Claims
 
1. A composition, comprising:
a hydrogel matrix including a light-absorbing additive material;
a first tubular channel and a second tubular channel defined in the hydrogel matrix, wherein the first tubular channel and the second tubular channel interpenetrate but do not intersect.