US 12,172,020 B2
Systems and related methods for optimization of multi-electrode nerve pacing
Joaquin Andres Hoffer, Anmore (CA); Gautam Sadarangani, Burnaby (CA); Marc-Andre Nolette, Burnaby (CA); Viral Thakkar, Burnaby (CA); and Bao Dung Tran, Vancouver (CA)
Assigned to Lungpacer Medical Inc., Vancouver (CA)
Filed by Lungpacer Medical Inc., Vancouver (CA)
Filed on Mar. 23, 2022, as Appl. No. 17/656,148.
Application 17/656,148 is a continuation of application No. 16/510,403, filed on Jul. 12, 2019, granted, now 11,311,730.
Application 16/510,403 is a continuation of application No. 15/427,924, filed on Feb. 8, 2017, granted, now 10,391,314, issued on Aug. 27, 2019.
Application 15/427,924 is a continuation of application No. 15/095,773, filed on Apr. 11, 2016, granted, now 9,597,509, issued on Mar. 21, 2017.
Application 15/095,773 is a continuation of application No. 14/600,763, filed on Jan. 20, 2015, granted, now 9,333,363, issued on May 10, 2016.
Claims priority of provisional application 61/929,901, filed on Jan. 21, 2014.
Prior Publication US 2022/0212013 A1, Jul. 7, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61N 1/36 (2006.01); A61B 5/00 (2006.01); A61B 5/0205 (2006.01); A61B 5/0245 (2006.01); A61B 5/05 (2021.01); A61B 5/08 (2006.01); A61B 5/145 (2006.01); A61B 5/24 (2021.01); A61B 5/287 (2021.01); A61B 5/389 (2021.01); A61N 1/05 (2006.01)
CPC A61N 1/36185 (2013.01) [A61B 5/0205 (2013.01); A61B 5/4836 (2013.01); A61B 5/4893 (2013.01); A61B 5/6852 (2013.01); A61B 5/7264 (2013.01); A61N 1/0551 (2013.01); A61N 1/3611 (2013.01); A61N 1/36139 (2013.01); A61B 5/0245 (2013.01); A61B 5/05 (2013.01); A61B 5/08 (2013.01); A61B 5/145 (2013.01); A61B 5/24 (2021.01); A61B 5/287 (2021.01); A61B 5/389 (2021.01); A61B 5/4818 (2013.01); A61B 2562/043 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A stimulation system comprising:
an electrode assembly including an electrode combination;
a sensor configured to monitor patient responses to electrical stimulation;
a stimulation control unit configured to:
deliver a plurality of stimulation pulses to the electrode combination, wherein each stimulation pulse includes a corresponding charge, and the corresponding charges differ among the plurality of stimulation pulses;
determine a relationship between the corresponding charges and respiratory muscle responses resulting from the corresponding charges, and between undelivered charges and respiratory muscle responses expected from the undelivered charges;
after determining the relationship, deliver therapeutic stimulation to the electrode combination;
using the relationship, determine an expected respiratory muscle response to the therapeutic stimulation; and
compare an actual respiratory muscle response to the expected respiratory muscle response.