US 12,172,015 B2
Non-invasive electrical stimulation for medical disorders
Bruce J. Simon, Santa Fe, NM (US); Joseph P. Errico, Palm Beach Gardens, FL (US); and John T. Raffle, Rockport, ME (US)
Assigned to ElectroCore, Inc., Rockaway, NJ (US)
Filed by ElectroCore, Inc., Rockaway, NJ (US)
Filed on Jan. 5, 2024, as Appl. No. 18/405,000.
Application 18/405,000 is a continuation of application No. 18/079,853, filed on Dec. 12, 2022.
Application 18/079,853 is a continuation of application No. 16/598,127, filed on Oct. 10, 2019.
Application 16/598,127 is a continuation of application No. 16/388,392, filed on Apr. 18, 2019, abandoned.
Application 16/388,392 is a continuation of application No. 14/462,605, filed on Aug. 19, 2014, granted, now 10,265,523.
Application 14/462,605 is a continuation of application No. 13/005,005, filed on Jan. 12, 2011, granted, now 8,868,177.
Application 13/005,005 is a continuation in part of application No. 12/964,050, filed on Dec. 9, 2010, abandoned.
Application 16/388,392 is a continuation in part of application No. 12/859,568, filed on Aug. 19, 2010.
Claims priority of provisional application 61/415,469, filed on Nov. 19, 2010.
Prior Publication US 2024/0139508 A1, May 2, 2024
Int. Cl. A61N 1/36 (2006.01); A61N 1/40 (2006.01); A61N 2/00 (2006.01); A61N 2/02 (2006.01)
CPC A61N 1/36025 (2013.01) [A61N 1/40 (2013.01); A61N 2/002 (2013.01); A61N 2/006 (2013.01); A61N 2/02 (2013.01); A61N 1/36114 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A method for treating a disorder in a patient, the method comprising:
positioning an electrode in contact with an outer skin surface of a neck of the patient;
transmitting, via the electrode, an electric current transcutaneously and non-invasively through the outer skin surface of the neck of the patient to generate an electrical impulse at or near a vagus nerve within the patient; and
wherein the electrical impulse comprises bursts of 2 to 20 pulses with each of the bursts comprising a frequency from about 15 Hz to about 50 Hz and with each of the pulses comprising a duration from about 20 microseconds to about 1000 microseconds, wherein the electrical impulse is sufficient to increase a release of retinoic acid.