CPC A61K 9/0068 (2013.01) [A61K 33/00 (2013.01); A61K 47/34 (2013.01); A61K 47/44 (2013.01)] | 46 Claims |
1. A bolus, comprising:
a core comprising:
metal;
a carrier; and
bromoform mixed with the carrier; and
a housing,
wherein:
one of the following holds:
the housing comprises poly lactic acid (PLA) and polybutylene adipate terephthalate (PBAT); or
the housing comprises poly lactic acid (PLA) and polybutylene succinate (PBS);
the bolus is configured to be administered to a ruminant animal; and
the bolus is configured so that, when the bolus is present in the rumen of the ruminant animal, bromoform passes through the housing and an effective amount of bromoform is delivered to the rumen of the ruminant animal over a period of time.
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