US 12,171,772 B2
Therapeutic uses of pharmaceutical compositions comprising cyclic boronic acid ester derivatives
Gavin Hirst, San Diego, CA (US); Raja Reddy, San Diego, CA (US); Scott J. Hecker, Del Mar, CA (US); Maxim Totrov, San Diego, CA (US); David C. Griffith, San Marcos, CA (US); Olga Lomovskaya, Mill Valley, CA (US); Michael N. Dudley, San Diego, CA (US); and Serge Henri Boyer, San Diego, CA (US)
Assigned to MELINTA SUBSIDIARY CORP., Parsippany, NJ (US)
Filed by Melinta Subsidiary Corp., Parsippany, NJ (US)
Filed on May 9, 2023, as Appl. No. 18/314,560.
Application 17/378,248 is a division of application No. 16/828,859, filed on Mar. 24, 2020, granted, now 11,090,319, issued on Aug. 17, 2021.
Application 16/828,859 is a division of application No. 16/188,982, filed on Nov. 13, 2018, granted, now 10,639,318, issued on May 5, 2020.
Application 16/188,982 is a division of application No. 15/935,782, filed on Mar. 26, 2018, granted, now 10,183,034, issued on Jan. 22, 2019.
Application 15/935,782 is a division of application No. 15/624,473, filed on Jun. 15, 2017, granted, now 10,004,758, issued on Jun. 26, 2018.
Application 15/015,002 is a division of application No. 13/953,647, filed on Jul. 29, 2013, granted, now 9,296,763, issued on Mar. 29, 2016.
Application 13/953,647 is a division of application No. 13/205,112, filed on Aug. 8, 2011, granted, now 8,680,136, issued on Mar. 25, 2014.
Application 18/314,560 is a continuation of application No. 17/378,248, filed on Jul. 16, 2021, granted, now 11,684,629.
Application 15/624,473 is a continuation of application No. 15/015,002, filed on Feb. 3, 2016, granted, now 9,694,025, issued on Jul. 4, 2017.
Claims priority of provisional application 61/488,655, filed on May 20, 2011.
Claims priority of provisional application 61/372,296, filed on Aug. 10, 2010.
Prior Publication US 2023/0277571 A1, Sep. 7, 2023
Int. Cl. A61K 31/69 (2006.01); A61K 9/00 (2006.01); A61K 31/407 (2006.01); A61K 31/4196 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01); A61K 31/546 (2006.01); A61K 45/06 (2006.01); C07F 5/02 (2006.01)
CPC A61K 31/69 (2013.01) [A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/407 (2013.01); A61K 31/4196 (2013.01); A61K 31/427 (2013.01); A61K 31/4439 (2013.01); A61K 31/546 (2013.01); A61K 45/06 (2013.01); C07F 5/025 (2013.01); Y02A 50/30 (2018.01)] 5 Claims
 
1. A crystalline form of 2-((3R,6S)-2-hydroxy-3-(2-(thiophen-2-yl)acetamido)-1,2-oxaborinan-6-yl)acetic acid:

OG Complex Work Unit Chemistry