US 12,171,488 B2
Treatment system with sensing and ablation catheter for treatment of heart rhythm disorders
Sanjiv M. Narayan, Palo Alto, CA (US); Dylan R. Montgomery, Murrieta, CA (US); Steven D. Thompson, Murrieta, CA (US); Jonathan S. Ciulla, Temecula, CA (US); Peter J. D'Aquanni, Murrieta, CA (US); Andy E. Denison, Temecula, CA (US); Melissa Donovan-Green, Temecula, CA (US); Jose Alvarado, Temecula, CA (US); Mahmood I. Alhusseini, Menlo Park, CA (US); and Bret A. Herscher, Cupertino, CA (US)
Assigned to PhysCade, Inc., Palo Alto, CA (US)
Filed by PhysCade, Inc., Palo Alto, CA (US)
Filed on Aug. 9, 2022, as Appl. No. 17/884,220.
Claims priority of provisional application 63/231,669, filed on Aug. 10, 2021.
Prior Publication US 2023/0049942 A1, Feb. 16, 2023
Int. Cl. A61B 18/14 (2006.01); A61B 18/00 (2006.01)
CPC A61B 18/1492 (2013.01) [A61B 2018/0016 (2013.01); A61B 2018/00267 (2013.01); A61B 2018/00357 (2013.01); A61B 2018/00642 (2013.01); A61B 2018/00702 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/00839 (2013.01); A61B 2018/00875 (2013.01); A61B 2218/002 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A treatment system for sensing and ablating tissue to treat a biological rhythm disorder, comprising:
a catheter for insertion into a patient, the catheter comprising:
a set of splines connected to form a surface that has a top side and a bottom side;
a plurality of ablation electrodes carried by the set of splines and arranged in a first array, the plurality of ablation electrodes configured to deliver ablation energy to modify tissue contributing to the biological rhythm disorder, and
a plurality of sensing electrodes carried by the set of splines and arranged in a second array, the plurality of sensing electrodes configured to sense electrical signals from the tissue corresponding to electrical activity of the tissue, at least one of the sensing electrodes having a conductive material on both the top side and the bottom side of the surface formed by the set of splines so that the at least one of the sensing electrodes is capable of sensing electrical signals from the top side or the bottom side,
wherein the plurality of sensing electrodes in the second array is arranged in a central region of electrodes and a peripheral region of electrodes enclosing the central region, wherein electrodes in the peripheral region of electrodes are spaced sparser than electrodes in the central region,
wherein the plurality of sensing electrodes is configured to monitor the electrical signals during delivery of the ablation energy; and
a control system configured to:
determine a personalized shape of a critical region in the tissue that contributes to the biological rhythm disorder based on the electrical signals sensed by the plurality of sensing electrodes,
determine an ablation pattern based on the personalized shape of the critical region, wherein the ablation pattern indicates a subset of the plurality of ablation electrodes to activate and an amount of ablation energy with which to activate each ablation electrode in the subset, and
instruct activation of at least the subset of ablation electrodes to achieve the ablation pattern.