US 11,852,642 B2
Methods and apparatus for HILN determination with a deep adaptation network for both serum and plasma samples
Venkatesh NarasimhaMurthy, Hillsborough, NJ (US); Vivek Singh, Princeton, NJ (US); Yao-Jen Chang, Princeton, NJ (US); Benjamin S. Pollack, Jersey City, NJ (US); and Ankur Kapoor, Plainsboro, NJ (US)
Assigned to Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US)
Appl. No. 17/278,285
Filed by Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US)
PCT Filed Sep. 19, 2019, PCT No. PCT/US2019/052012
§ 371(c)(1), (2) Date Mar. 19, 2021,
PCT Pub. No. WO2020/061369, PCT Pub. Date Mar. 26, 2020.
Claims priority of provisional application 62/733,985, filed on Sep. 20, 2018.
Prior Publication US 2021/0334972 A1, Oct. 28, 2021
Int. Cl. G06T 7/00 (2017.01); G01N 35/00 (2006.01); G06F 18/2431 (2023.01); G06V 10/764 (2022.01); G06V 10/82 (2022.01)
CPC G01N 35/00732 (2013.01) [G06F 18/2431 (2023.01); G06T 7/0014 (2013.01); G06V 10/764 (2022.01); G06V 10/82 (2022.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30024 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A method of characterizing a specimen container, comprising:
processing pixel data of an image of a specimen container containing a specimen therein to determine whether the specimen container includes a serum portion or a plasma portion using a classification network executing on a computer; and
transforming pixel data of an image determined by the classification network to include a serum portion into transformed-pixel data that matches pixel data of a previously-collected image of a plasma portion having an appearance that corresponds to an appearance of the serum portion without affecting any HILN (hemolytic, icteric, lipemic, and normal) characteristics present in the pixel data of the image using a transformation network executing on the computer.