US 11,851,674 B2
Three-dimensional scaffold structures with selectively functionalized polymer systems, their use and process for their manufacture
Herbert Wolter, Wuerzburg (DE); Somchith Nique, Wuerzburg (DE); Sebastian Hasselmann, Wuerzburg (DE); Caroline Kopittke, Wuerzburg (DE); Doris Heinrich, Wuerzburg (DE); and Johannes Schwaiger, Wuerzburg (DE)
Assigned to Fraunhofer-Gesllschaft zur Foerderung der angewandten Forschung e.V., Munich (DE)
Filed by Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V., Munich (DE)
Filed on Nov. 14, 2019, as Appl. No. 16/683,954.
Claims priority of application No. 102018128576 (DE), filed on Nov. 14, 2018.
Prior Publication US 2020/0149000 A1, May 14, 2020
Int. Cl. C08F 122/10 (2006.01); C12N 5/00 (2006.01); C08F 230/08 (2006.01)
CPC C12N 5/0068 (2013.01) [C08F 122/10 (2013.01); C08F 230/085 (2020.02)] 13 Claims
 
1. A three-dimensional scaffold structure, comprising:
scaffold structure parts made of a polymer system and fluid-filled open spaces between said scaffold structure parts with a minimum extent of 50 nm in each spatial direction;
the scaffold structure configured to be filled with water as a fluid to consist of at least 50 percent by volume of water at room temperature;
said polymer system is obtained by treating a starting material with electromagnetic radiation that is locally targeted to form the scaffold structure having open spaces, said starting material containing precursor molecules of formula (I) or partially condensated species thereof:

OG Complex Work Unit Chemistry
wherein the radicals and the indices have the following meaning:
B is a straight-chain or branched or cyclic organic radical having at least one C═C double bond and 4 to 100 carbon atoms;
X is hydrogen, halogen, hydroxy, alkoxy, acyloxy, alkylcarbonyl, alkoxycarbonyl or NR42;
R is alkyl, alkenyl, aryl, alkylaryl or arylalkyl;
R2 is OH, COOH, NR42, NR42H+ or SH or a derivative thereof;
R4 is hydrogen, alkyl, aryl or alkylaryl;
RRg is the backbone of a straight-chain or branched hydrocarbon bonded to the Si atom, where the backbone may be interrupted by heteroatoms or heteroatom-containing groups;
a=1, 2 or 3;
b=0, 1 or 2;
a+b=3; and
c=1, 2, 3 or 4.