US 11,850,592 B2
Particle manipulation system with multisort valve
John S. Foster, Santa Barbara, CA (US); Kevin Shields, Santa Barbara, CA (US); and Mehran Hoonejani, Goleta, CA (US)
Assigned to Owl biomedical, Inc., Goleta, CA (US)
Filed by Owl biomedical, Inc., Goleta, CA (US)
Filed on Feb. 11, 2020, as Appl. No. 16/787,114.
Application 16/787,114 is a continuation in part of application No. 15/810,232, filed on Nov. 13, 2017.
Prior Publication US 2020/0179931 A1, Jun. 11, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. B01L 3/00 (2006.01)
CPC B01L 3/502761 (2013.01) [B01L 3/50273 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/049 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0622 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A cell sorting device comprising a sorting magnet and at least one particle manipulation device, wherein the particle manipulation device is formed on a fabrication surface of a fabrication substrate, comprising:
at least one fluid channel, wherein the sorting magnet and the particle manipulation device are in fluid communication with one another through at least one fluid channel;
a microfabricated, movable member formed on the fabrication substrate, and having a first diverting surface, wherein the movable member moves from a first position to a second position in response to a force applied to the movable member, wherein the motion is substantially in a plane parallel to the fabrication surface of the fabrication substrate;
an sample inlet channel formed in the substrate and through which a fluid flows, the fluid including at least one target particle and non-target material, wherein the flow in the sample inlet channel is substantially parallel to the fabrication surface;
a plurality of output channels into which the microfabricated member diverts the fluid, and wherein the flow in at least one of the output channels is not parallel to the plane, and wherein at least one output channel is located directly below or above at least a portion of the microfabricated member over at least a portion of its motion.