US 11,850,332 B2
Method for treating tissue
Frederick E. Shelton, IV, Hillsboro, OH (US); Michael J. Vendely, Lebanon, OH (US); Jason L. Harris, Lebanon, OH (US); and Jacqueline Anim, Springboro, OH (US)
Assigned to Cilag GmbH International, Zug (CH)
Filed by Cilag GmbH International, Zug (CH)
Filed on Mar. 30, 2021, as Appl. No. 17/217,252.
Prior Publication US 2022/0313874 A1, Oct. 6, 2022
Int. Cl. A61B 17/072 (2006.01); A61B 17/00 (2006.01); A61B 17/115 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); A61K 38/47 (2006.01); A61K 33/00 (2006.01); A61K 33/40 (2006.01)
CPC A61L 31/146 (2013.01) [A61B 17/07292 (2013.01); A61K 33/00 (2013.01); A61K 33/40 (2013.01); A61K 38/47 (2013.01); A61L 31/145 (2013.01); A61L 31/16 (2013.01); A61B 17/1155 (2013.01); A61B 2017/00004 (2013.01); A61B 2017/00061 (2013.01); A61B 2017/00084 (2013.01); A61B 2017/00199 (2013.01); A61B 2017/00893 (2013.01); A61B 2017/07271 (2013.01); A61B 2017/07285 (2013.01); A61L 2300/10 (2013.01); A61L 2300/11 (2013.01); A61L 2300/114 (2013.01); A61L 2300/254 (2013.01); A61L 2300/442 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method for treating tissue, comprising:
securing, by one or more staples, a biocompatible porous polymer adjunct material to tissue, the adjunct material receiving at least one physiological element released from the tissue during healing progression of the tissue, and the adjunct material exhibiting a first stiffness in compression that is approximately constant during a first time period from contact with the tissue and exhibiting a second stiffness in compression during a second time period following the first time period, the second stiffness being less than the first stiffness and decreasing with time as a function of at least one of oxidation, enzyme-catalyzed hydrolysis, and change of pH resulting from interaction with the at least one physiological element.