	US 11,850,331 B2
	Devices with anti-thrombogenic and anti-microbial treatment
Nisha Gupta, Audubon, PA (US); Chuanting You, Sinking Spring, PA (US); Kamna Giare-Patel, Wyomissing, PA (US); and Kevin Sechrist, Womelsdorf, PA (US)
Assigned to Teleflex Medical Incorporated, Morrisville, NC (US)
Appl. No. 14/774,602
Filed by TELEFLEX MEDICAL INCORPORATED, Morrisville, NC (US)
PCT Filed Mar. 10, 2014, PCT No. PCT/US2014/022574 § 371(c)(1), (2) Date Sep. 10, 2015, PCT Pub. No. WO2014/164487, PCT Pub. Date Oct. 9, 2014.
Claims priority of provisional application 61/879,623, filed on Sep. 18, 2013.
Claims priority of provisional application 61/776,104, filed on Mar. 11, 2013.
Prior Publication US 2016/0015863 A1, Jan. 21, 2016
Int. Cl. A61L 29/08 (2006.01); C09D 175/04 (2006.01); A61L 29/16 (2006.01); D01D 5/24 (2006.01); A61M 25/00 (2006.01)

CPC A61L 29/085 (2013.01) [A61L 29/16 (2013.01); C09D 175/04 (2013.01); D01D 5/24 (2013.01); A61L 2300/206 (2013.01); A61L 2300/404 (2013.01); A61L 2300/42 (2013.01); A61M 2025/0056 (2013.01)]

23 Claims

1. A medical device adapted for contact with a vessel or cavity in the body, the medical device including a tubular portion, comprising:

an external coating or impregnation comprising alexidine in an amount that is 200 μg/cm²to 300 μg/cm²; and

an internal coating or impregnation comprising alexidine in an amount that is less concentrated than the external coating or impregnation.