US 11,850,035 B2
Breath analysis methodology for medical diagnostics
Sylvia Daunert, Miami, FL (US); Jeramy Lee Rueff Baum, Miami, FL (US); Carl Ivan Schulman, Miami, FL (US); Sapna K. Deo, Miami, FL (US); Emre Dikici, Miami, FL (US); Chitvan Killawala, Miami, FL (US); Kelly Withum, Miami, FL (US); and Kevin Miller, Miami, FL (US)
Assigned to UNIVERSITY OF MIAMI, Miami, FL (US)
Appl. No. 15/733,998
Filed by UNIVERSITY OF MIAMI, Miami, FL (US)
PCT Filed Jun. 25, 2019, PCT No. PCT/US2019/038891
§ 371(c)(1), (2) Date Dec. 1, 2020,
PCT Pub. No. WO2020/005874, PCT Pub. Date Jan. 2, 2020.
Claims priority of provisional application 62/756,851, filed on Nov. 7, 2018.
Claims priority of provisional application 62/689,729, filed on Jun. 25, 2018.
Prior Publication US 2021/0228104 A1, Jul. 29, 2021
Int. Cl. A61B 5/08 (2006.01); G16H 40/63 (2018.01); A61B 5/18 (2006.01); A61B 5/00 (2006.01); G01N 33/497 (2006.01)
CPC A61B 5/082 (2013.01) [A61B 5/18 (2013.01); A61B 5/4845 (2013.01); A61B 5/6893 (2013.01); G01N 33/4972 (2013.01); G16H 40/63 (2018.01); A61B 2503/22 (2013.01); A61B 2562/04 (2013.01); G01N 2033/4975 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A method for detecting a condition in an individual by analyzing the individual's breath, the method comprising:
capturing, by one or more sensors, data associated with the breath of the individual, wherein capturing the data associated with the breath of the individual comprises:
generating heat by a heater associated with the one or more sensors while the one or more sensors are exposed to the breath of the individual;
measuring a first resistance detected by the one or more sensors while the one or more sensors are exposed to the breath of the individual;
modifying the heat generated by the heater associated with the one or more sensors while the one or more sensors are exposed to the breath of the individual, after measuring the first resistance; and
measuring a second resistance detected by the one or more sensors while the one or more sensors are exposed to the breath of the individual, after modifying the heat generated by the heater;
analyzing, by a processor, the data captured by the one or more sensors to identify one or more volatile organic compound biomarkers; and
determining, by the processor, based on the identified one or more volatile organic compound biomarkers, a condition associated with the individual.