US 11,841,189 B1
Disposable for a spray drying system
Robert R. Andrews, Norfolk, MA (US); Herman E. Snyder, W. Lafayette, IN (US); William J. Merritt, Danvers, MA (US); Evan P. Ordway, Salem, MA (US); Clair Strohl, Emmaus, PA (US); and Russell Barron, Boston, MA (US)
Assigned to Velico Medical, Inc., Beverly, MA (US)
Filed by Velico Medical, Inc., Beverly, MA (US)
Filed on Sep. 15, 2022, as Appl. No. 17/945,124.
Int. Cl. F26B 3/12 (2006.01); A61K 35/16 (2015.01)
CPC F26B 3/12 (2013.01) [A61K 35/16 (2013.01)] 24 Claims
OG exemplary drawing
 
1. A spray drying disposable device having a spray drying head and a plasma drying chamber, for use in a spray drying system that comprises the spray drying disposable device and a spray drying apparatus, the spay drying system having a drying gas source that provides a drying gas, a plasma source that provides a plasma and a pressurized aerosol gas source that provides a pressurized aerosol gas, the spray drying disposable device comprising:
A) the spray drying head comprising:
i) a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source, wherein spray drying nozzle comprises a vortex generator having a plurality of channels and a plurality of pads that are curved to allow the pressurized aerosol gas to flow in a vortex pattern, wherein, when in use, the pressurized aerosol gas atomizes the plasma entering the drying chamber to thereby obtain atomized plasma droplets;
ii) a plenum having a drying gas inlet in communication with the drying gas source, wherein, when in use, the drying gas resides in the plenum with uniform air pressure, wherein the plenum supports the nozzle assembly;
iii) a baffle plate forming a floor of the plenum having one or more drying gas jets, wherein, when in use, the one or more drying gas jets provide the drying gas to the drying chamber;
B) the drying chamber, attached to the baffle plate, wherein, when in use, atomized plasma droplets evaporate when coming into contact with the drying gas emitted from the one or more drying gas jets to thereby obtain dried plasma particles and humid air;
C) a capture filter, residing in the drying chamber, wherein the capture filter captures the dried plasma particles and allows the humid air to pass; and
D) a gas outlet, wherein said gas outlet is attached to an exhaust port of the spray drying system during operation, wherein the humid air flows through the gas outlet.