US 11,840,514 B2
Catalysts and methods for enantioselective conjugate addition of amines to unsaturated electrophiles
Karl A. Scheidt, Evanston, IL (US); and Brice Uno, Highland Park, IL (US)
Assigned to Northwestern University, Evanston, IL (US)
Filed by Northwestern University, Evanston, IL (US)
Filed on Sep. 21, 2020, as Appl. No. 17/027,687.
Application 17/027,687 is a division of application No. 16/448,821, filed on Jun. 21, 2019, granted, now 10,781,172.
Claims priority of provisional application 62/687,912, filed on Jun. 21, 2018.
Prior Publication US 2021/0002221 A1, Jan. 7, 2021
Int. Cl. C07D 207/416 (2006.01); B01J 31/18 (2006.01); C07D 405/12 (2006.01); C07D 401/04 (2006.01)
CPC C07D 207/416 (2013.01) [B01J 31/185 (2013.01); C07D 401/04 (2013.01); C07D 405/12 (2013.01); B01J 2231/348 (2013.01); B01J 2531/23 (2013.01)] 7 Claims
 
1. A compound of a formula:

OG Complex Work Unit Chemistry
wherein
R1 is selected from the group consisting of alkyl, cycloalkyl, alkenyl, and —CH2—R1 ,
wherein R1′ is selected from the group consisting of aryl, arylalkyl, and cycloalkyl, and
R1′ is optionally substituted at one or more positions with alkyl, halo, or alkoxy;
R2 is hydrogen or alkyl; and
R3 is hydrogen, alkyl, alkoxy, or halo.