US 11,839,766 B2
Neuromodulation system
Mathieu Scheltienne, Eindhoven (NL); Edoardo Paoles, Eindhoven (NL); Jeroen Tol, Eindhoven (NL); and Jurriaan Bakker, Eindhoven (NL)
Assigned to Onward Medical N.V., Eindhoven (NL)
Filed by ONWARD MEDICAL N.V., Eindhoven (NL)
Filed on Nov. 13, 2020, as Appl. No. 17/098,183.
Claims priority of application No. 19211698 (EP), filed on Nov. 27, 2019.
Prior Publication US 2021/0154475 A1, May 27, 2021
Int. Cl. A61N 1/36 (2006.01); A61N 1/05 (2006.01); A61B 34/10 (2016.01); G16H 20/40 (2018.01); G16H 30/20 (2018.01); A61B 90/00 (2016.01); A61B 17/00 (2006.01)
CPC A61N 1/36062 (2017.08) [A61B 34/10 (2016.02); A61N 1/0551 (2013.01); A61N 1/36067 (2013.01); A61N 1/36175 (2013.01); G16H 20/40 (2018.01); G16H 30/20 (2018.01); A61B 2017/00039 (2013.01); A61B 2017/00044 (2013.01); A61B 2034/104 (2016.02); A61B 2034/105 (2016.02); A61B 2034/107 (2016.02); A61B 2090/373 (2016.02); A61B 2090/374 (2016.02); A61B 2090/3762 (2016.02); A61N 1/36103 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A neuromodulation system comprising:
at least one input module for inputting patient data into the neuromodulation system;
at least one model calculation and building module for building a patient model, the patient model comprising three-dimensional reconstructions of dorsal roots of the patient, the three-dimensional reconstructions coupled with electrophysiology models of multiple types of nerve fibers included in the three-dimensional reconstructions of the dorsal roots; and
at least one computation module for calculating an impact of neuromodulation by determining a difference between a target and a simulated percentage activation of nerve fibers for multiple combinations of dorsal root and nerve fiber type using the three-dimensional reconstructions and the coupled electrophysiology models.