US 11,839,681 B2
Charcoal-containing double capsule and method for manufacturing same
Chan-Jae Shin, Daejeon (KR); Tae-Sung Ko, Sejong (KR); Hyun-Gyu Shin, Daejeon (KR); and Jeong-Ho Park, Daejeon (KR)
Assigned to BIOGENICS, INC., Daejeon (KR)
Appl. No. 15/734,294
Filed by BIOGENICS, INC., Daejeon (KR)
PCT Filed Aug. 31, 2018, PCT No. PCT/KR2018/010149
§ 371(c)(1), (2) Date Dec. 2, 2020,
PCT Pub. No. WO2020/013380, PCT Pub. Date Jan. 16, 2020.
Claims priority of application No. 10-2018-0081457 (KR), filed on Jul. 13, 2018.
Prior Publication US 2021/0220253 A1, Jul. 22, 2021
Int. Cl. A61Q 11/00 (2006.01); A61Q 19/00 (2006.01); A61K 9/24 (2006.01); A61K 8/11 (2006.01); A61K 9/50 (2006.01); A61K 9/48 (2006.01); A61K 8/97 (2017.01); A61K 8/25 (2006.01); A61K 8/29 (2006.01); A61K 8/73 (2006.01)
CPC A61K 8/97 (2013.01) [A61K 8/25 (2013.01); A61K 8/29 (2013.01); A61K 8/732 (2013.01); A61Q 11/00 (2013.01); A61Q 19/00 (2013.01); A61K 2800/41 (2013.01); A61K 2800/56 (2013.01)] 12 Claims
 
1. A charcoal-containing double capsule comprising consisting of:
a softening agent, a second binder, a coloring agent, and a primary capsule containing a dispersing agent, charcoal powder, and a first binder, wherein the charcoal powder is bound to the first binder,
wherein the primary capsule and the coloring agent are bound to the second binder,
wherein the first binder is a modified starch selected from the group consisting of acetylated distarch adipate, acetylated distarch phosphate, starch sodium octenyl succinate, distarch phosphate, monostarch phosphate, phosphated distarch phosphate, starch acetate, and hydroxypropyl distarch phosphate; or a natural starch selected from the group consisting of a wheat starch, a rice starch, a potato starch, and a corn starch,
wherein the dispersing agent is any one selected from the group consisting of polyglyceryl-2 oleyl ether, polyglyceryl-6 pentaoleate, polyoxyethylene glyceryl monostearate, and polyglyceryl-10 stearate,
wherein the softening agent is any one selected from the group consisting of a lauric acid and a palmitic acid,
wherein the coloring agent is a mixture of titanium dioxide and silica, and
wherein the primary capsule contains 70-94 wt % of the charcoal powder, with respect to 100 wt % of the primary capsule.