	US 12,492,176 B2
	Process for preparation of 2, 5-furan dicarboxylic acid from 5-hydroxymethyl furfural
Paresh Laxmikant Dhepe, Maharashtra (IN); Kalyani Gajananrao Sonone, Maharashtra (IN); and Priya Laxmanrao Lokhande, Maharashtra (IN)
Assigned to COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH, New Delhi (IN)
Appl. No. 18/041,458
Filed by COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH, New Delhi (IN)
PCT Filed Aug. 10, 2021, PCT No. PCT/IN2021/050766 § 371(c)(1), (2) Date Feb. 13, 2023, PCT Pub. No. WO2022/034613, PCT Pub. Date Feb. 17, 2022.
Claims priority of application No. 202011034406 (IN), filed on Aug. 11, 2020.
Prior Publication US 2023/0295102 A1, Sep. 21, 2023
Int. Cl. C07D 307/68 (2006.01); B01J 23/89 (2006.01); B01J 29/06 (2006.01); B01J 37/00 (2006.01); B01J 37/02 (2006.01); B01J 37/04 (2006.01); B01J 37/08 (2006.01)

CPC C07D 307/68 (2013.01) [B01J 23/8986 (2013.01); B01J 29/06 (2013.01); B01J 37/0036 (2013.01); B01J 37/0236 (2013.01); B01J 37/04 (2013.01); B01J 37/08 (2013.01); B01J 2235/00 (2024.01); B01J 2235/05 (2024.01); B01J 2235/10 (2024.01); B01J 2235/15 (2024.01); B01J 2235/30 (2024.01)]

11 Claims

1. A process for synthesis of 2, 5-furan dicarboxylic acid from crude 5-hydroxymethyl furfural, the process comprising the steps of:

a) reacting a glucose with a zeolite catalyst in a solvent at a temperature in the range of 165° C.-185° C. for a period of 5-6 hrs to obtain crude 5-hydroxymethyl furfural;

b) optionally, purifying the crude 5-hydroxymethyl furfural as obtained in step (a) with a solvent by extraction method to obtain pure 5-hydroxymethyl furfural;

c) reacting the 5-hydroxymethyl furfural as obtained in step (a) or (b) with a mixed metal oxide catalyst in a solvent at a temperature in the range of 120° C.-140° C. for 1-24 hrs under 10-20 bar O₂/air pressure in the presence of a base to obtain 2,5-furan dicarboxylic acid.