	US 12,491,146 B1
	Skin brightening compositions with thiopyridinone compound
Catherine Chiou, Saddle Brook, NJ (US); Hungta Lin, Teaneck, NJ (US); Mariko Hasebe, New York, NY (US); Nicholas David Stebbins, Clark, NJ (US); and Ritesh Kumar Sinha, Linden, NJ (US)
Assigned to L'OREAL, Paris (FR)
Filed by L'OREAL, Paris (FR)
Filed on Feb. 4, 2025, as Appl. No. 19/045,297.
Claims priority of provisional application 63/737,499, filed on Dec. 20, 2024.
Int. Cl. A61K 8/49 (2006.01); A61K 8/34 (2006.01); A61K 8/46 (2006.01); A61Q 19/02 (2006.01)

CPC A61K 8/4933 (2013.01) [A61K 8/345 (2013.01); A61K 8/463 (2013.01); A61Q 19/02 (2013.01); A61K 2800/28 (2013.01); A61K 2800/5424 (2013.01)]

20 Claims

1. A cosmetic composition comprising:

(a) about 0.05 to about 5 wt. % of 2-mercaptonicotinoyl glycine;

(b) about 5 to about 25 wt. % of one or more acyl glycinate surfactants;

(c) about 0.05 to about 5 wt. % of one or more salts providing divalent cations having a charge density of about 40 to about 200 C/mm3 and a water solubility of at least 400 g/L;

(d) about 0.5 to about 6 wt. % of one or more anionic polymers;

(e) about 35 to about 60 wt. % of glycerin;

(f) about 15 to about 50 wt. % of water; and

(g) about 0.1 to about 3 wt. % of one or more thiosulfate and/or bisulfite reducing agents;

wherein the composition has a viscosity of about 25,000 cP to about 300,000 cP at 25° C. and a shear rate of 1 s⁻1, and all percentages by weight are based on a total weight of the composition.