| CPC A61B 18/14 (2013.01) [A61B 2018/0047 (2013.01); A61B 2018/00589 (2013.01); A61B 2018/00875 (2013.01); A61B 2018/126 (2013.01); A61B 2018/1425 (2013.01); A61B 2018/1467 (2013.01); A61B 2562/028 (2013.01)] | 18 Claims |

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1. A method of inducing collagen regeneration in the skin of a patient, the method comprising:
measuring the thickness of at least one layer of the skin of the patient with a non-invasiveprobe which includes an ultrasonic array having a plurality of ultrasound integrated circuits;
contacting the skin of the patient and delivering electrical energy to the skin of the patient via an electrode array having a plurality of electrodes wherein each ultrasound integrated circuit of the ultrasound array is situated between at least two electrodes of the electrode array; and
adjusting via a processor, based on a measurement of the probe, one or more operating parameters of the electrode array selected from the group consisting of: a waveform frequency of the electrical energy, an amplitude of the waveform, a duration of the electrical energy deliver, and the depth of penetration into the skin of the at least one electrode.
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