| CPC A61B 17/22012 (2013.01) [A61M 25/10182 (2013.11); A61M 25/10184 (2013.11); A61M 25/104 (2013.01); A61B 2017/00154 (2013.01); A61B 2017/22001 (2013.01); A61B 2017/22062 (2013.01)] | 13 Claims |

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1. A method for treating an at least partially calcified lesion in a target blood vessel, comprising:
introducing a balloon catheter within the target blood vessel, an inflatable balloon of the balloon catheter positioned to impart pressure from the inflatable balloon to the calcified lesion;
delivering fluid from a fluid reservoir in operative communication with the inflatable balloon for providing a first pressure magnitude of the inflatable balloon against the target blood vessel;
using a controller over a first pressure pulse period for creating a first series of pressure pulses and thus applying a first plurality of pressure magnitudes within the first pressure pulse period to the calcified lesion with a reduced pressure period defined by and between successive magnitudes of the first plurality of pressure magnitudes, each pressure pulse of the first series of pressure pulses creating a pressure magnitude that is of a higher pressure than the first pressure magnitude;
transferring the first series of pressure pulses and first plurality of pressure magnitudes from the inflatable balloon to the target blood vessel for applying the higher pressure by each pressure pulse of the first series of pressure pulses to the target blood vessel and breaking up calcification of the calcified lesion; and
reducing the pressure applied by the inflatable balloon to the target blood vessel for a first decompression period that is longer than any reduced pressure period after the application of the first plurality of pressure magnitudes.
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