US 12,156,989 B2
Systems, apparatuses and methods for occlusion detection using pump operation measurement
Ling Zheng, Acton, MA (US); Mojtaba Kashef, Boxford, MA (US); Uzair Siddiqui, Jersey City, NJ (US); Jinyan Li, Chelmsford, MA (US); Kepei Sun, Andover, MA (US); Joseph Iskandar, Roslindale, MA (US); and Elizabeth Gurin, Franklin Lakes, NJ (US)
Assigned to BECTON, DICKINSON AND COMPANY, Franklin Lakes, NJ (US)
Appl. No. 16/967,330
Filed by Becton, Dickinson and Company, Franklin Lakes, NJ (US)
PCT Filed Jan. 29, 2019, PCT No. PCT/US2019/015622
§ 371(c)(1), (2) Date Aug. 4, 2020,
PCT Pub. No. WO2019/156852, PCT Pub. Date Aug. 15, 2019.
Claims priority of provisional application 62/764,998, filed on Aug. 20, 2018.
Claims priority of provisional application 62/663,682, filed on Apr. 27, 2018.
Claims priority of provisional application 62/626,909, filed on Feb. 6, 2018.
Prior Publication US 2021/0030953 A1, Feb. 4, 2021
Int. Cl. A61M 5/168 (2006.01); A61M 5/142 (2006.01)
CPC A61M 5/16831 (2013.01) [A61M 5/14212 (2013.01); A61M 2005/14208 (2013.01); A61M 2005/16863 (2013.01); A61M 2205/18 (2013.01); A61M 2205/3331 (2013.01)] 22 Claims
OG exemplary drawing
 
1. An infusion device with integral occlusion sensing comprising:
a pump comprising a chamber configured with at least one port to receive fluid into the chamber from a reservoir and through which the fluid flows out of the chamber, and a pumping mechanism configured to operate for a plurality of pump cycles wherein each pump cycle among the plurality of pump cycles comprises an aspirate stroke and a dispense stroke, and to control aspiration of a volume of the fluid into the chamber during the aspirate stroke of each pump cycle among the plurality of pump cycles and to control dispensing of a volume of the fluid from the chamber during the dispense stroke of each pump cycle among the plurality of pump cycles;
a pump measurement device configured to generate pump measurements related to a respective stroke in each pump cycle among the plurality of pump cycles, the respective stroke chosen from the aspirate stroke of each pump cycle among the plurality of pump cycles performed by the pump, and the dispense stroke of each pump cycle among the plurality of pump cycles performed by the pump;
a processing device configured to analyze the pump measurements and determine when the pump measurements comprise a plurality of the pump measurements that satisfy a predetermined metric designated as an indication of an occlusion; and
wherein the pump measurement device comprises a current sensing device configured to detect a pumping mechanism current during the respective stroke in each pump cycle among the plurality of pump cycles;
wherein the pump measurements correspond to the pumping mechanism current detected during the respective stroke in each pump cycle among the plurality of pump cycles; and
wherein the predetermined metric comprises an average pumping mechanism current among the respective strokes that exceeds a designated current value that is higher than an average value of the pumping mechanism current when no occlusion is occurring in the pump, the processing device being configured to determine the average pumping mechanism current as a mean of values of the pumping mechanism current over time.