US 12,156,907 B2
Recombinant vector for expressing virus-like particles in plant and method for preparation of vaccine composition containing circovirus-like particles by using same
Eun-Ju Sohn, Gyeongsangbuk-do (KR); Yongjik Lee, Gyeongsangbuk-do (KR); and Sangmin Lee, Gyeongsangbuk-do (KR)
Assigned to BIOAPPLICATIONS INC., Gyeongsangbuk-do (KR)
Filed by BIOAPPLICATIONS INC., Gyeongsangbuk-do (KR)
Filed on May 14, 2021, as Appl. No. 17/320,369.
Application 17/320,369 is a continuation in part of application No. PCT/KR2019/013581, filed on Oct. 16, 2019.
Claims priority of application No. 10-2018-0141184 (KR), filed on Nov. 15, 2018; and application No. 10-2019-0127987 (KR), filed on Oct. 15, 2019.
Prior Publication US 2021/0330780 A1, Oct. 28, 2021
Int. Cl. A61K 39/12 (2006.01); A61K 39/00 (2006.01); C12N 15/82 (2006.01)
CPC A61K 39/12 (2013.01) [C12N 15/8205 (2013.01); A61K 2039/55505 (2013.01); C12N 2750/10023 (2013.01); C12N 2750/10034 (2013.01); C12N 2750/10051 (2013.01)] 19 Claims
 
1. A recombinant vector for plant expression, comprising a polynucleotide encoding a RuBisCO transit peptide comprising the amino acid sequence of SEQ ID NO: 1 and a polynucleotide consisting of the nucleotide sequence of SEQ ID NO: 4 encoding a porcine circovirus type 2 (PCV2) capsid protein.