US 11,834,451 B2
Compositions and methods for inhibiting virus protein 2C activity and for preventing and treating non-polio enterovirus infection
Jun Wang, Tucson, AZ (US); and Naoya Kitamura, Tucson, AZ (US)
Assigned to Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US)
Filed by Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US)
Filed on Mar. 28, 2022, as Appl. No. 17/705,984.
Claims priority of provisional application 63/167,417, filed on Mar. 29, 2021.
Prior Publication US 2022/0306627 A1, Sep. 29, 2022
Int. Cl. C07D 471/04 (2006.01)
CPC C07D 471/04 (2013.01) 9 Claims
 
1. A compound encompassed within Formula I:

OG Complex Work Unit Chemistry
including pharmaceutically acceptable salts, solvates, and/or prodrugs thereof,
wherein R1 is selected from hydrogen, CH3,

OG Complex Work Unit Chemistry
wherein R2 is selected from the group consisting of hydrogen and CH3;
wherein R3 is selected from the group consisting of hydrogen,

OG Complex Work Unit Chemistry
 and
wherein R4 is selected from the group consisting of hydrogen, CH3,

OG Complex Work Unit Chemistry