US 11,833,246 B1
Rectal gel with date palm phenolics and vanillic acid
Hany Ezzat Khalil Ahmed, Al-Ahsa (SA); Hairul Islam Mohamed Ibrahim, Al-Ahsa (SA); and Krishnaraj Thirugnanasambantham, Al-Ahsa (SA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Jul. 5, 2023, as Appl. No. 18/218,438.
Application 18/218,438 is a division of application No. 18/113,721, filed on Feb. 24, 2023.
Int. Cl. A61K 9/06 (2006.01); A61K 47/46 (2006.01); A61K 31/515 (2006.01); A61K 47/42 (2017.01); A61K 47/38 (2006.01); A61K 47/12 (2006.01); A61K 31/5513 (2006.01); A61P 1/00 (2006.01)
CPC A61K 9/06 (2013.01) [A61K 31/515 (2013.01); A61K 31/5513 (2013.01); A61K 47/12 (2013.01); A61K 47/38 (2013.01); A61K 47/42 (2013.01); A61K 47/46 (2013.01); A61P 1/00 (2018.01)] 12 Claims
OG exemplary drawing
 
1. A method for treating a bowel disease, disorder, or condition in a patient in need thereof, the method comprising:
topically administering a therapeutically effective amount of a gel composition to a rectum of the patient;
the gel composition comprising:
about 0.1 to about 2.5 wt. % of an anti-epileptic agent;
about 0.8 to about 2.0% wt. % of a collagen complexed with a date palm extract of Khalas cultivar and carboxymethylcellulose;
including about 10 to about 50 μg/mL of vanillic acid;
about 0.1 to about 0.3 μg of stearic acid; and
water;
wherein all wt. % are based on g/100 g of the gel composition;
wherein the bowel disease, disorder, or condition is selected from the group consisting of rectal complications, rectal wounds, and a combination thereof.