AS A RESULT OF REEXAMINATION, IT HAS BEEN DETERMINED THAT:
Claims 1-20 are cancelled.
At the time of issuance and publication of this certificate, the patent remains subject to pending reissue application number 18/135,473 filed Apr. 17, 2023. The claim content of the patent may be subsequently revised if a reissue patent is issued from the reissue application.
1. A method of treating overweight or obesity in a subject having an increased risk of adverse cardiovascular out-comes, the method comprising:
treating the subject for overweight or obesity by administering to the subject a daily dose of 32 mg of sustained release naltrexone, or a pharmaceutically acceptable salt thereof, and 360 mg bupropion, or a pharmaceutically acceptable salt thereof, for a period of at least 12 weeks.