US 12,488,705 B2
Synthetic thrombus model for learning the surgical removal of a blood clot in the context of a treatment simulation
Nadine MacMillan, Hamburg (DE); Dieter Krause, Buchholz (DE); Jens Fiehler, Hamburg (DE); Helena Guerreiro, Hamburg (DE); and Anna Kyselyova, Hamburg (DE)
Assigned to TECHNISCHE UNIVERSITÄT HAMBURG, Hamburg (DE)
Appl. No. 18/560,045
Filed by TECHNISCHE UNIVERSITÄT HAMBURG, Hamburg (DE)
PCT Filed May 10, 2022, PCT No. PCT/EP2022/062649
§ 371(c)(1), (2) Date Nov. 9, 2023,
PCT Pub. No. WO2022/238408, PCT Pub. Date Nov. 17, 2022.
Claims priority of application No. 10 2021 112 467.0 (DE), filed on May 12, 2021.
Prior Publication US 2024/0290224 A1, Aug. 29, 2024
Int. Cl. G09B 23/30 (2006.01); C08K 5/47 (2006.01); C08L 5/12 (2006.01); C08L 83/04 (2006.01); G09B 23/34 (2006.01)
CPC G09B 23/34 (2013.01) [C08K 5/47 (2013.01); C08L 5/12 (2013.01); C08L 83/04 (2013.01); G09B 23/303 (2013.01); C08L 2203/02 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A synthetic thrombus model for learning a surgical removal of a blood clot from a blood vessel using mechanical thrombectomy in a simulation of various stroke scenarios in a training model, the synthetic thrombus model comprising:
an elongated base body formed from an elastically deformable main material having a Shore A hardness in a range of 0 to 10, wherein the elastically deformable main material comprises agarose or silicone rubber; and
an adhesive present in an amount of 5 to 40% by weight, wherein the adhesive comprises chloromethylisothiazolinone (CMIT), a mixture of CMIT and methylisothiazolinone (MIT), or both, and wherein the adhesive is combined with the elastically deformable main material to improve at least the hardness and fragmentation properties of the synthetic thrombus model.