US 12,487,441 B2
Systems and methods for fluorescence microscopy channel crosstalk mitigation
Kevin Ferguson, Beaverton, OR (US)
Assigned to ARACELI BIOSCIENCES INC., Tigard, OR (US)
Filed by ARACELI BIOSCIENCES INC., Tigard, OR (US)
Filed on Jun. 6, 2023, as Appl. No. 18/330,190.
Application 18/330,190 is a continuation in part of application No. 18/194,449, filed on Mar. 31, 2023.
Prior Publication US 2024/0329382 A1, Oct. 3, 2024
Int. Cl. G02B 21/36 (2006.01); G01N 21/64 (2006.01)
CPC G02B 21/367 (2013.01) [G01N 21/6458 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/10064 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method, comprising:
accumulating a plurality of weighting constant values and variance data to determine a weighting constant of a weighted interference signal of a microscopy image;
determining the weighted interference signal of the microscopy image based on the weighting constant;
removing the weighted interference signal from an overall image signal of the microscopy image; and
determining a recovered image signal based on removal of the weighted interference signal from the overall image signal.