US 12,487,304 B2
Signal saturation method for achieving spatial selection under non-uniform field, and medium
Chao Wang, Chengdu (CN); Hai Luo, Chengdu (CN); Min Wu, Chengdu (CN); Xiao Chen, Chengdu (CN); and Ziyue Wu, Chengdu (CN)
Assigned to WUXI MARVEL STONE HEALTHCARE CO., LTD., Wuxi (CN)
Filed by WUXI MARVEL STONE HEALTHCARE CO., LTD., Wuxi (CN)
Filed on Apr. 3, 2025, as Appl. No. 19/169,043.
Application 19/169,043 is a continuation of application No. PCT/CN2022/130114, filed on Nov. 4, 2022.
Claims priority of application No. 202211313839.1 (CN), filed on Oct. 25, 2022.
Prior Publication US 2025/0258259 A1, Aug. 14, 2025
Int. Cl. G01R 33/387 (2006.01); G01R 33/341 (2006.01)
CPC G01R 33/387 (2013.01) [G01R 33/341 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A signal saturation method for achieving spatial selection under a non-uniform field, comprising following steps:
setting a corresponding magnetization preparation module based on a distance between a target saturation region and a surface coil under a non-uniform field;
transmitting, by the surface coil, a first main pulse sequence, or sequentially transmitting a first magnetization preparation module and a first main pulse sequence, to acquire a first echo signal, and storing the first echo signal as a first dataset;
sequentially transmitting, by the surface coil, a second magnetization preparation module and a second main pulse sequence to acquire a second echo signal, and storing the second echo signal as a second dataset; and
processing the first dataset and the second dataset to saturate a signal in the target saturation region to achieve the spatial selection, wherein the step of processing the first dataset and the second dataset to saturate the signal in the target saturation region to achieve the spatial selection comprises:
performing, according to a corresponding synthetic calculation equation, data synthetic calculation on the first dataset and the second dataset to saturate the signal in the target saturation region to achieve the spatial selection, wherein the synthetic calculation equation at least comprises:

OG Complex Work Unit Math
wherein Ssync denotes synthesized data; S1 denotes the first dataset; S2 denotes the second dataset; and W denotes a weighting coefficient, and
wherein the weighting coefficient W is obtained by:
placing a phantom with a same thickness as the target saturation region in the target saturation region as an experimental subject;
scanning the experimental subject separately through the first main pulse sequence, the first magnetization preparation module and the first main pulse sequence, and the second magnetization preparation module and the second main pulse sequence to obtain a first test set and a second test set; and
calculating, based on the first test set and the second test set, the weighting coefficient W as follows:
minwwS′1+S′2  (7)
wherein S′1 denotes the first test set; and S′2 denotes the second test set.