	US 12,487,239 B2
	Biochemical probes attached to epoxy-based resins
Alexei Boris Shvets, Gorham, ME (US); Darrin Leighton Ramsdell, Portland, ME (US); Michelle M. Straub, Yarmouth, ME (US); Yerramilli V. S. N. Murthy, Scarborough, ME (US); Phillip Sheldon Smith, Gorham, ME (US); and Anne Catherine Fitzpatrick, Portland, ME (US)
Assigned to IDEXX LABORATORIES, INC., Westbrook, ME (US)
Filed by IDEXX LABORATORIES, INC., Westbrook, ME (US)
Filed on Feb. 28, 2022, as Appl. No. 17/681,973.
Claims priority of provisional application 63/288,018, filed on Dec. 10, 2021.
Claims priority of provisional application 63/155,472, filed on Mar. 2, 2021.
Prior Publication US 2022/0283159 A1, Sep. 8, 2022
Int. Cl. G01N 33/569 (2006.01); G01N 33/53 (2006.01)

CPC G01N 33/56911 (2013.01) [G01N 33/5308 (2013.01); G01N 2800/26 (2013.01)]

26 Claims

1. A method of making a substrate for biological analysis comprising:

(i) providing a substrate that has a surface comprising an epoxy-based resin and

(ii) contacting a biomolecule probe with the substrate that has a surface comprising an epoxy-based resin so that the biomolecule probe bonds directly to the epoxy-based resin;

wherein the substrate that has a surface comprising an epoxy-based resin is washed with dimethylsulfoxide (DMSO) before the biomolecule probe is contacted with the substrate that has a surface comprising an epoxy-based resin.