US 12,485,420 B2
Systems and methods for multi-junction particle sorting in injection-molded articles
Saurabh Vyawahare, Mountain View, CA (US); Andrew Homyk, Belmont, CA (US); Michael Brundage, Lincoln, MA (US); Srinivas Hanasoge, Foster City, CA (US); and Junjia Ding, San Mateo, CA (US)
Assigned to Verily Life Sciences LLC, Dallas, TX (US)
Filed by Verily Life Sciences LLC, South San Francisco, CA (US)
Filed on Apr. 11, 2022, as Appl. No. 17/658,781.
Claims priority of provisional application 63/196,379, filed on Jun. 3, 2021.
Prior Publication US 2022/0388004 A1, Dec. 8, 2022
Int. Cl. B01L 3/00 (2006.01); B29D 22/00 (2006.01); G01N 15/14 (2024.01); G01N 15/10 (2024.01); G01N 15/149 (2024.01)
CPC B01L 3/502784 (2013.01) [B01L 3/502715 (2013.01); B29D 22/00 (2013.01); G01N 15/1484 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/088 (2013.01); B01L 2400/02 (2013.01); G01N 2015/1006 (2013.01); G01N 15/149 (2024.01)] 27 Claims
OG exemplary drawing
 
1. A method of producing a microfluidic sorting apparatus, the method comprising:
providing an injection-molded substrate comprising a network of channels, wherein the network of channels comprises a plurality of sort junctions, wherein each of the plurality of sort junctions comprises a primary channel connected to a sorting outlet channel and a medium supply channel, and wherein the network of channels further comprises an electrode channel, wherein the electrode channel is adjacent each sorting outlet channel;
bonding an insulating film to an upper surface of the substrate to cover the network of channels; and
depositing a conductive film on the insulating film to produce a ground film for each electrode channel;
wherein the substrate is separated and distinct from the conductive film.