US 12,485,132 B2
GPX4 inhibitors and senolytic compounds and uses thereof
Michael Hadd, San Jose, CA (US); and Paul Keitz, Redwood City, CA (US)
Assigned to Rubedo Life Sciences, Inc., Sunnyvale, CA (US)
Filed by Rubedo Life Sciences, Inc., Sunnyvale, CA (US)
Filed on Jun. 24, 2025, as Appl. No. 19/247,553.
Application 19/247,553 is a continuation of application No. 18/678,791, filed on May 30, 2024.
Claims priority of provisional application 63/572,605, filed on Apr. 1, 2024.
Claims priority of provisional application 63/567,749, filed on Mar. 20, 2024.
Claims priority of provisional application 63/505,128, filed on May 31, 2023.
Prior Publication US 2025/0319109 A1, Oct. 16, 2025
Int. Cl. C07J 41/00 (2006.01); A61K 31/575 (2006.01); A61K 31/704 (2006.01); A61P 39/00 (2006.01); C07H 15/18 (2006.01); C07J 31/00 (2006.01); C07J 43/00 (2006.01)
CPC A61K 31/704 (2013.01) [A61K 31/575 (2013.01); A61P 39/00 (2018.01); C07H 15/18 (2013.01); C07J 31/006 (2013.01); C07J 41/0005 (2013.01); C07J 41/0016 (2013.01); C07J 43/003 (2013.01)] 10 Claims
 
1. A compound having the structure:

OG Complex Work Unit Chemistry
or pharmaceutically acceptable salts, hydrates or solvates thereof.