US 12,485,064 B2
Systems and methods for measuring oxygen concentration for lung preservation
Ben Bulka, North Waltham, MA (US); Arkady Shinder-Lerner, North Waltham, MA (US); William Lucas Churchill, Bolton, MA (US); Michael Tajima, North Waltham, MA (US); and Pratik Patel, North Waltham, MA (US)
Assigned to Paragonix Technologies, Inc., Waltham, MA (US)
Filed by Paragonix Technologies, Inc., North Waltham, MA (US)
Filed on Aug. 23, 2024, as Appl. No. 18/813,851.
Claims priority of provisional application 63/631,923, filed on Apr. 9, 2024.
Claims priority of provisional application 63/578,796, filed on Aug. 25, 2023.
Prior Publication US 2025/0064052 A1, Feb. 27, 2025
Int. Cl. A61H 31/00 (2006.01); A01N 1/142 (2025.01); A01N 1/146 (2025.01); A01N 1/148 (2025.01); A01N 1/16 (2025.01); A01N 1/165 (2025.01)
CPC A61H 31/00 (2013.01) [A01N 1/142 (2025.01); A01N 1/146 (2025.01); A01N 1/148 (2025.01); A01N 1/16 (2025.01); A01N 1/165 (2025.01)] 19 Claims
OG exemplary drawing
 
1. A system for preserving a lung based on oxygen concentration, the system comprising:
a transport container configured to receive a lung;
a lung adapter configured to seal with an airway of the lung;
a sensor configured to measure an oxygen concentration in the lung during ex-vivo preservation, the sensor configured to be positioned within the transport container and in fluid communication with the airway of the lung;
a gas source configured to be in fluid communication with the lung adapter; and
a pump configured to pump gas from the gas source to the lung adapter and the airway of the lung when the oxygen concentration is below an oxygen threshold.
 
16. A method for preserving a lung based on oxygen concentration, the method comprising:
providing a transport container configured to receive a lung;
sealing an airway of the lung to a lung adapter of the transport container;
measuring, using a sensor positioned within the transport container and in fluid communication with the airway of the lung, an oxygen concentration in the lung during ex-vivo preservation; and
delivering, using a pump, oxygen to the lung through the lung adapter when the oxygen concentration is below an oxygen threshold.