US 12,484,948 B2
Flow regulating assembly and flexible cryoprobe with adjustable flow
Chi Yang, Shanghai (CN); and Zhaohua Chang, Shanghai (CN)
Assigned to ACCU TARGET MEDIPHARMA (SHANGHAI) CO., LTD., Shanghai (CN)
Appl. No. 17/927,341
Filed by ACCUTARGET MEDIPHARMA (SHANGHAI) CO., LTD., Shanghai (CN)
PCT Filed Feb. 9, 2021, PCT No. PCT/CN2021/076191
§ 371(c)(1), (2) Date Nov. 22, 2022,
PCT Pub. No. WO2021/169800, PCT Pub. Date Sep. 2, 2021.
Claims priority of application No. 202010111100.7 (CN), filed on Feb. 24, 2020.
Prior Publication US 2023/0293220 A1, Sep. 21, 2023
Int. Cl. A61B 18/02 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01)
CPC A61B 18/02 (2013.01) [A61B 2017/00367 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00744 (2013.01); A61B 2018/0262 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A flow regulating assembly, comprising a mandrel, wherein a regulating chamber is provided in the mandrel;
a first end portion of the mandrel is provided with a large air outlet, a side wall of the mandrel is provided with a small air outlet, and the large air outlet has an inner diameter less than that of the regulating chamber;
a second end portion of the mandrel is connected to a front end of a J-T slot, and a rear end of the J-T slot is connected to a bypass pipe;
a sealing member is arranged in the regulating chamber, and the sealing member has an outer diameter less than the inner diameter of the regulating chamber and greater than the inner diameter of the large air outlet;
the sealing member is connected to one end of a traction member, and the other end of the traction member is led out through the bypass pipe;
a tail end of the bypass pipe is provided with a sealing assembly, the sealing assembly comprises a sealing ring, and an inner diameter of the sealing ring matches an outer diameter of the traction member, to allow the traction member to pass through;
wherein the sealing member axially moves in the regulating chamber under an action of the traction member, and a quantity of effective air outlets that are in the large air outlet and the small air outlet and are in communication with the bypass pipe is changed by adjusting a position of the sealing member;
at least one small air outlet is provided;
wherein when the sealing member is at the large air outlet in the first end portion of the mandrel, the large air outlet is closed, and the small air outlet is in communication with the bypass pipe to be used as the effective air outlet for gas venting; in this case, a formed flow is minimum, and the flow regulating assembly is configured to introduce carbon dioxide or nitrous oxide to implement a cryoadhesion mode; and
when the sealing member moves to the second end portion of the mandrel under traction of the traction member, the large air outlet and the small air outlet are in communication with the bypass pipe to be used as the effective air outlets for gas venting; in this case, a formed flow is maximum, and the flow regulating assembly is configured to introduce nitrogen or argon to implement a cryoablation mode.