US 12,484,865 B2
Selective internal radiation therapy mapping via microbeads with different contrast materials
Alois Regensburger, Poxdorf (DE)
Assigned to Varian Medical Systems, Inc., Palo Alto, CA (US)
Filed by Varian Medical Systems, Inc., Palo Alto, CA (US)
Filed on Feb. 2, 2024, as Appl. No. 18/431,905.
Prior Publication US 2025/0248671 A1, Aug. 7, 2025
Int. Cl. A61B 6/00 (2024.01); A61B 6/12 (2006.01); A61B 6/42 (2024.01); A61B 6/50 (2024.01); A61K 49/04 (2006.01); G16H 20/40 (2018.01)
CPC A61B 6/12 (2013.01) [A61B 6/4241 (2013.01); A61B 6/481 (2013.01); A61B 6/504 (2013.01); A61B 6/5235 (2013.01); A61K 49/0419 (2013.01); G16H 20/40 (2018.01)] 21 Claims
OG exemplary drawing
 
1. A method comprising:
providing a mixture of smaller contrast-loaded microbeads and larger contrast-loaded microbeads in a known ratio;
waiting a first period of time after the mixture has been administered to a treatment site; and
after the first period of time, determining a first shunt fraction of the mixture by correlating the known ratio to a diffused ratio of the smaller contrast-loaded microbeads to the larger contrast-loaded microbeads in the treatment site.