US 12,484,838 B2
Large dynamic range detector for gingivitis detection
Olaf Thomas Johan Antonie Vermeulen, Oss (NL); Alan James Davie, Cambridge (GB); and Steven Charles Deane, Cambridge (GB)
Assigned to KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
Appl. No. 17/275,035
Filed by KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
PCT Filed Sep. 2, 2019, PCT No. PCT/EP2019/073322
§ 371(c)(1), (2) Date Mar. 10, 2021,
PCT Pub. No. WO2020/053011, PCT Pub. Date Mar. 19, 2020.
Claims priority of provisional application 62/729,455, filed on Sep. 11, 2018.
Prior Publication US 2022/0054079 A1, Feb. 24, 2022
Int. Cl. A61B 5/00 (2006.01); G02B 6/42 (2006.01)
CPC A61B 5/4552 (2013.01) [A61B 5/0075 (2013.01); A61B 5/0088 (2013.01); G02B 6/4215 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A system for detecting tissue inflammation, comprising:
a light emitter configured to emit light at a tissue region within a mouth of an individual;
at least four wavelength-sensitive photodetectors configured to detect optical signals diffusely reflected through the tissue region, wherein each of the at least four wavelength-sensitive photodetectors comprises a filter and a photodiode, wherein the photodiodes are configured to convert the optical signals into currents respectively output by the photodiodes, wherein the photodiodes are stacked on top of each other to generate current differential signals from differences between the currents respectively output by adjacent photodiodes;
at least four amplifiers corresponding to the photodiodes of the at least four wavelength-sensitive photodetectors, wherein the current differential signals are input to the at least four amplifiers corresponding to the photodiodes, wherein the generation of the current differential signals removes unwanted components from the optical signals prior to amplification; and
a controller configured to detect tissue inflammation at the tissue region based on outputs from the at least four amplifiers.