US 12,484,830 B2
Neural interface system and method
Selim Eminoglu, Alameda, CA (US)
Assigned to Science Corporation, Alameda, CA (US)
Filed by Science Corporation, Alameda, CA (US)
Filed on Apr. 1, 2025, as Appl. No. 19/097,539.
Claims priority of provisional application 63/572,837, filed on Apr. 1, 2024.
Prior Publication US 2025/0302358 A1, Oct. 2, 2025
Int. Cl. A61B 5/294 (2021.01); A61B 5/30 (2021.01)
CPC A61B 5/294 (2021.01) [A61B 5/30 (2021.01)] 18 Claims
OG exemplary drawing
 
1. An integrated circuit system, comprising:
a neural interface module comprising an array of neural interface elements, wherein each neural interface element comprises:
a first electrode input configured to receive a signal from a first neuron;
a second electrode input configured to receive a signal from a second neuron;
a coupling capacitor;
a differential low-noise amplifier configured to record a differential signal from the first electrode input and the second electrode input, wherein one of the first electrode input or the second electrode input is used as a reference; and
an analog sample-and-hold configured to store the signal from the low-noise amplifier;
wherein the array of neural interface elements comprises a first subset of neural interface elements configured for neural spike recording and a second subset of neural interface elements configured for neural Local Field Potential (LFP) recording, wherein the coupling capacitors of the second subset of neural interface elements are larger than the coupling capacitors of the first subset of neural interface elements.