US 12,153,014 B2
Compositions, methods, kits and devices for molecular analysis
Jen-Kuei Liu, Palo Alto, CA (US); Bharti Solanki, Antioch, CA (US); Hans Michael Wenz, Redwood City, CA (US); Frank Mercer, Belmont, CA (US); Cevat Akin, San Bruno, CA (US); Achim Karger, Foster City, CA (US); Annelise Barron, Woodside, CA (US); and Scott Mack, Boulder Creek, CA (US)
Assigned to Integenx, Inc., Pleasanton, CA (US); and Life Technologies Corporation, Carlsbad, CA (US)
Filed by LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US); and INTEGENX INC., Carlsbad, CA (US)
Filed on Feb. 10, 2023, as Appl. No. 18/108,471.
Application 18/108,471 is a division of application No. 16/615,804, granted, now 11,619,608, previously published as PCT/US2018/033972, filed on May 22, 2018.
Claims priority of provisional application 62/675,057, filed on May 22, 2018.
Claims priority of provisional application 62/509,560, filed on May 22, 2017.
Prior Publication US 2023/0314369 A1, Oct. 5, 2023
Int. Cl. G01N 27/447 (2006.01); C08L 33/26 (2006.01)
CPC G01N 27/44747 (2013.01) [C08L 33/26 (2013.01); C08L 2203/02 (2013.01); C08L 2205/025 (2013.01)] 17 Claims
 
1. A method for separating one or more biomolecules in an analyte, the method comprising:
(i) providing a separation medium, wherein the separation medium comprises
(a) at least one polymer or copolymer,
(b) an aqueous solvent or aqueous buffer,
wherein the separation medium exhibits functional stability for electrophoresis after storage at a temperature of at least about 15° C. for at least one week; and
(ii) passing an analyte through the separation medium under an applied electric field to enable electrophoretic separation of one or more biomolecules,
wherein the analyte comprises nucleic acid and wherein the nucleic acid comprises one or more short tandem repeats (STRs).