	US 12,151,242 B2
	Methods for analyzing biological samples in a fluidic device comprising generating a polymer matrix from precursors at specific locations comprising biological components
Tarun Kumar Khurana, Palo Alto, CA (US); Ali Agah, Palo Alto, CA (US); Yir-Shyuan Wu, Palo Alto, CA (US); and Filiz Gorpe Yasar, Palo Alto, CA (US)
Assigned to Cellanome, Inc., Foster City, CA (US)
Filed by Cellanome, Inc., Palo Alto, CA (US)
Filed on Mar. 1, 2024, as Appl. No. 18/593,787.
Application 18/593,787 is a continuation of application No. 18/219,545, filed on Jul. 7, 2023, granted, now 12,030,047.
Application 18/219,545 is a continuation of application No. PCT/US2022/011720, filed on Jan. 7, 2022.
Claims priority of provisional application 63/253,500, filed on Oct. 7, 2021.
Claims priority of provisional application 63/135,463, filed on Jan. 8, 2021.
Prior Publication US 2024/0198332 A1, Jun. 20, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C12Q 1/68 (2018.01); B01L 3/00 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/6874 (2018.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01)

CPC B01L 3/502715 (2013.01) [B01L 3/502707 (2013.01); B01L 3/502761 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6874 (2013.01); G01N 33/54386 (2013.01); G01N 33/6842 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/12 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0883 (2013.01); B01L 2300/12 (2013.01); B01L 2300/163 (2013.01); B01L 2300/18 (2013.01); C12Q 2600/158 (2013.01); G01N 2570/00 (2013.01)]

30 Claims

1. A method for processing a biological sample, comprising:

(a) introducing the biological sample into a fluidic device, wherein the biological sample comprises a biological component;

(b) introducing polymer precursors into the fluidic device;

(d) selectively polymerizing the polymer precursors to generate a polymer matrix from the polymer precursors within the fluidic device, wherein the polymer matrix at least partially encapsulates the biological component.