Methods, systems, and devices for pairing vagus nerve stimulation with motor therapy in stroke patients
Michael P. Kilgard, Richardson, TX (US); Navzer Engineer, Plano, TX (US); David Michael Pierce, Plano, TX (US); and Robert L. Rennaker, Sachse, TX (US)
Assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US)
Filed by Board of Regents, The University of Texas System, Austin, TX (US)
Filed on May 2, 2023, as Appl. No. 18/310,935.
Application 18/310,935 is a continuation of application No. 15/382,970, filed on Dec. 19, 2016, granted, now 11,638,824.
Application 15/382,970 is a continuation of application No. 14/252,727, filed on Apr. 14, 2014, granted, now 9,522,272, issued on Dec. 20, 2016.
Application 14/252,727 is a continuation of application No. 13/651,349, filed on Oct. 12, 2012, granted, now 8,700,145, issued on Apr. 15, 2014.
Application 18/310,935 is a continuation in part of application No. 13/095,570, filed on Apr. 27, 2011, granted, now 9,089,703, issued on Jul. 8, 2015.
Application 13/095,570 is a continuation in part of application No. 12/485,040, filed on Jun. 15, 2009, granted, now 9,089,707, issued on Jul. 8, 2015.
Claims priority of provisional application 61/699,470, filed on Sep. 11, 2012.
Claims priority of provisional application 61/614,369, filed on Mar. 22, 2012.
Claims priority of provisional application 61/598,185, filed on Feb. 13, 2012.
Claims priority of provisional application 61/558,287, filed on Nov. 10, 2011.
Claims priority of provisional application 61/627,532, filed on Oct. 13, 2011.
Claims priority of provisional application 61/328,621, filed on Apr. 27, 2010.
Claims priority of provisional application 61/077,648, filed on Jul. 2, 2008.
Claims priority of provisional application 61/078,954, filed on Jul. 8, 2008.
Claims priority of provisional application 61/086,116, filed on Aug. 4, 2008.
Claims priority of provisional application 61/149,387, filed on Feb. 3, 2009.
Prior Publication US 2023/0264023 A1, Aug. 24, 2023
1. A motor-deficit-therapeutic method for treatment of a patient who has hemiparesis, the method comprising:
providing, to the patient afflicted with a hemiparesis, a neurostimulator configured to stimulate a vagus nerve of the patient using electrical, magnetic, optical, acoustic or mechanical stimulation; and
initiating stimulation of the vagus nerve by the neurostimulator so that at least a portion of the stimulation occurs at least during performance by the patient of a motor therapy session which is hemiparesis-therapeutic, thereby improving the patient's hemiparesis.