US 12,150,993 B2
Hypericin-PVP complex with high hypericin content
Andreas Kubin, Vienna (AT)
Assigned to HYPERICUM LIFESCIENCE GMBH, Vienna (AT)
Appl. No. 17/255,349
Filed by Hypericum LifeScience GmbH, Vienna (AT)
PCT Filed Jul. 12, 2019, PCT No. PCT/EP2019/068775
§ 371(c)(1), (2) Date Dec. 22, 2020,
PCT Pub. No. WO2020/011960, PCT Pub. Date Jan. 16, 2020.
Claims priority of application No. 18183435 (EP), filed on Jul. 13, 2018.
Prior Publication US 2021/0260192 A1, Aug. 26, 2021
Int. Cl. A61K 41/00 (2020.01); A01N 25/10 (2006.01); A01N 35/04 (2006.01); A61K 47/58 (2017.01)
CPC A61K 41/0057 (2013.01) [A01N 25/10 (2013.01); A01N 35/04 (2013.01); A61K 47/58 (2017.08)] 5 Claims
 
1. A method for the production of a complex comprising polyvinylpyrrolidone (PVP) and hypericin or a hypericin salt, the method comprising, providing a mixture of hypericin or a hypericin salt and PVP, and heating the mixture to a temperature which is above a glass transition temperature of the PVP to form the complex,
wherein the complex comprises greater than 6% by weight of the hypericin or the hypericin salt with respect to a total weight of the complex.