US 12,150,900 B2
Corneal lenticular incision using a femtosecond laser with optimized pulse energy and scan line steps
Nima Khatibzadeh, San Jose, CA (US); Li Bing, San Jose, CA (US); and Hong Fu, Pleasanton, CA (US)
Assigned to AMO Development, LLC, Irvine, CA (US)
Filed by AMO Development, LLC, Santa Ana, CA (US)
Filed on Nov. 30, 2021, as Appl. No. 17/457,034.
Prior Publication US 2023/0165717 A1, Jun. 1, 2023
Int. Cl. A61F 9/008 (2006.01); A61B 18/20 (2006.01)
CPC A61F 9/00827 (2013.01) [A61F 9/00836 (2013.01); A61B 2018/20353 (2017.05); A61B 2018/20355 (2017.05); A61F 2009/00872 (2013.01); A61F 2009/00897 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An ophthalmic surgical laser system comprising:
a laser source configured to generate a pulsed laser beam comprising a plurality of laser pulses;
a laser delivery system configured to deliver the pulsed laser beam to a target tissue in a subject's eye;
a high frequency scanner configured to scan the pulsed laser beam back and forth at a predefined frequency;
an XY-scanner configured to deflect the pulsed laser beam, the XY-scanner being separate from the high frequency scanner;
a Z-scanner configured to modify a depth of a focus of the pulsed laser beam; and
a controller configured to control the laser source, the high frequency scanner, the XY-scanner and the Z-scanner to successively form a plurality of sweeps which collectively form at least one lenticular incision of a lens in the subject's eye, the lens having a curved surface that defines an apex and a Z axis passing through the apex, wherein each sweep is formed by:
controlling the laser source to generate the pulsed laser beam having a pulse energy of 40 nJ to 70 nJ;
controlling the high frequency scanner to deflect the pulsed laser beam to form a scan line, the scan line being a straight line having a predefined length and being tangential to a parallel of latitude of the lens, the parallel of latitude being a circle on the surface of the lens that is perpendicular to the Z axis and has a defined distance to the apex, and
controlling the XY-scanner and the Z-scanner to move the scan line along a meridian of longitude of the lens, the meridian of longitude being a curve that passes through the apex and has a defined angular position around the Z axis, wherein the scan line is moved at a sweeping speed that produces a scan line step of between 1.7 μm and 2.3 μm, the scan line step being a distance between a center of consecutive scan lines;
wherein the plurality of sweeps are successively formed one after another along the respective meridians of longitude which are different from one another.
 
10. A method for creating a lenticular incision using an ophthalmic surgical laser system, the method comprising the steps of:
generating, by a laser source, a pulsed laser beam comprising a plurality of laser pulses;
delivering, by a laser delivery system, the pulsed laser beam to a target tissue in a subject's eye;
scanning, by a high frequency scanner, the pulsed laser beam back and forth at a predefined frequency;
deflecting, by an XY-scanner, the pulsed laser beam, the XY-scanner being separate from the high frequency scanner;
modifying, by a Z-scanner, a depth of a focus of the pulsed laser beam; and
controlling, by a controller, the laser source, the high frequency scanner, the XY-scanner and the Z-scanner to successively form a plurality of sweeps which collectively form at least one lenticular incision of a lens in the subject's eye, the lens having a curved surface that defines an apex and a Z axis passing through the apex, including forming each sweep by:
controlling the laser source to generate the pulsed laser beam having a pulse energy of 40 nJ to 70 nJ;
controlling the high frequency scanner to deflect the pulsed laser beam to form a scan line, the scan line being a straight line having a predefined length and being tangential to a parallel of latitude of the lens, the parallel of latitude being a circle on the surface of the lens that is perpendicular to the Z axis and has a defined distance to the apex, and
controlling the XY-scanner and the Z-scanner to move the scan line along a meridian of longitude of the lens, the meridian of longitude being a curve that passes through the apex and has a defined angular position around the Z axis, wherein the scan line is moved at a sweeping speed that produces a scan line step of between 1.7 μm and 2.3 μm, the scan line step being a distance between a center of consecutive scan lines;
wherein the plurality of sweeps are successively formed one after another along the respective meridians of longitude which are different from one another.
 
19. An ophthalmic surgical laser system comprising:
a laser source configured to generate a pulsed laser beam comprising a plurality of laser pulses;
a laser delivery system configured to deliver the pulsed laser beam to a target tissue in a subject's eye;
a high frequency scanner configured to scan the pulsed laser beam back and forth at a predefined frequency;
an XY-scanner configured to deflect the pulsed laser beam, the XY-scanner being separate from the high frequency scanner;
a Z-scanner configured to modify a depth of a focus of the pulsed laser beam; and
a controller configured to control the laser source, the high frequency scanner, the XY-scanner and the Z-scanner to successively form a plurality of sweeps which collectively form a bed cut in the target tissue, wherein each sweep is formed by:
controlling the laser source to generate the pulsed laser beam having a pulse energy of 40 nJ to 70 nJ;
controlling the high frequency scanner to deflect the pulsed laser beam to form a scan line, the scan line being a straight line having a predefined length, and
controlling the XY-scanner to move the scan line along a predetermined direction, wherein the scan line is moved at a sweeping speed that produces a scan line step of between 1.7 μm and 2.3 μm, the scan line step being a distance between a center of consecutive scan lines.