US 12,480,941 B2
Rapid mobile screening and triage for infections and infection severity
Joy Parr Drach, Pontiac, IL (US); Brendan Smith, Cary, NC (US); Tobias M. Heineck, Durham, NC (US); Stefano Bresolin, Garner, NC (US); Rodolfo R. Rodriguez, Cary, NC (US); Danielle Stewart Noel, Raleigh, NC (US); Brian Pike, Durham, NC (US); Oleg Kakhovsky, Raleigh, NC (US); and Jasper N. Pollard, Durham, NC (US)
Assigned to Advanced Animal Diagnostics, Inc., Morrisville, NC (US)
Appl. No. 17/905,990
Filed by Advanced Animal Diagnostics, Inc., Morrisville, NC (US)
PCT Filed Mar. 12, 2021, PCT No. PCT/US2021/022167
§ 371(c)(1), (2) Date Sep. 9, 2022,
PCT Pub. No. WO2021/183927, PCT Pub. Date Sep. 16, 2021.
Claims priority of provisional application 62/989,283, filed on Mar. 13, 2020.
Prior Publication US 2023/0096475 A1, Mar. 30, 2023
Int. Cl. G01N 33/50 (2006.01); G01N 15/05 (2006.01); G01N 15/1433 (2024.01); G01N 21/64 (2006.01); G01N 33/49 (2006.01)
CPC G01N 33/5094 (2013.01) [G01N 15/05 (2013.01); G01N 15/1433 (2024.01); G01N 21/6458 (2013.01); G01N 33/49 (2013.01); G01N 2201/0221 (2013.01)] 20 Claims
OG exemplary drawing
 
19. A portable apparatus, comprising:
a processor;
a hematology analyzer comprising a single camera, the hematology analyzer in communication with the processor; and
a tangible, non-transitory memory configured to communicate with the processor, the tangible, non-transitory memory having instructions stored thereon that, in response to execution by the processor, cause the processor to perform operations comprising:
receiving from the hematology analyzer, a stack of serial focal plane images of a blood sample in a chamber from a plurality of fields of view of the chamber;
creating a virtual three dimensional image of the blood sample from selected ones of the stacks of serial focal plane images; and
analyzing the virtual three dimensional image to identify blood formed elements within the blood sample.