US 12,480,849 B2
Bioreactor device determining properties of biological sample, has holding element and cantilever
Alessia Pisanu, Huningue (FR); Anna Marsano, Binningen (CH); Giuseppe Isu, Turin (IT); Conradin Döbelin, Liestal (CH); and Giuseppe Pisani, Bülach (CH)
Assigned to UNIVERSITÄT BASEL, Basel (CH)
Appl. No. 17/598,346
Filed by UNIVERSITÄT BASEL, Basel (CH)
PCT Filed Mar. 27, 2020, PCT No. PCT/EP2020/058819
§ 371(c)(1), (2) Date Sep. 27, 2021,
PCT Pub. No. WO2020/193777, PCT Pub. Date Oct. 1, 2020.
Claims priority of application No. 19165964 (EP), filed on Mar. 28, 2019.
Prior Publication US 2022/0187176 A1, Jun. 16, 2022
Int. Cl. G01N 3/08 (2006.01); C12M 1/00 (2006.01); C12M 1/42 (2006.01)
CPC G01N 3/08 (2013.01) [G01N 2203/0017 (2013.01); G01N 2203/0019 (2013.01); G01N 2203/04 (2013.01)] 20 Claims
OG exemplary drawing
 
1. Apparatus (100) for determining properties of a sample (110) arranged in at least one receptacle (130) of a container device (120) comprising:
an actuator (30) which is configured to be coupled to the sample (110) via at least one holding element (34) which is configured to hold the sample (110), wherein the actuator (30) is configured to apply a mechanical stimulus to the sample (110) via the at least one holding element (34),
a force sensing device (20) which is configured to be coupled to the sample (110) via at least one cantilever (22),
a frame (1), wherein the actuator (30) and the force sensing device (20) are configured to be mounted to the frame (1), and wherein the frame (1) is configured to be arranged on the container device (120),
wherein
when the actuator (30) and the force sensing device (20) are mounted to the frame (1) the at least one holding element (34) and the at least one cantilever (22) are arranged in the at least one receptacle (130) when the frame (1) is arranged on the container device (120), wherein the at least one holding element (34) comprises a bending stiffness which is greater than a bending stiffness of the at least one cantilever (22).