US 12,479,637 B2
Closure system and kit
Nariye Salibryam Cavusoglu Ataman, Basel (CH); Monica De Bardi, Basel (CH); Guido Drees, Basel (CH); Maria Enterrios Quintana, Basel (CH); Joseph Alexander Martin, Basel (CH); Holger Roehl, Basel (CH); Thomas Peter Stuedeli, Basel (CH); Eszter Voros, Basel (CH); Neil Bentley Cammish, Basel (CH); and Marcel Sigrist, Basel (CH)
Assigned to HOFFMANN-LA ROCHE INC., Little Falls, NJ (US)
Appl. No. 18/257,894
Filed by HOFFMANN-LA ROCHE INC., Little Falls, NJ (US)
PCT Filed Dec. 17, 2021, PCT No. PCT/EP2021/086611
§ 371(c)(1), (2) Date Jun. 16, 2023,
PCT Pub. No. WO2022/129585, PCT Pub. Date Jun. 23, 2022.
Claims priority of application No. 20215176 (EP), filed on Dec. 17, 2020.
Prior Publication US 2024/0051719 A1, Feb. 15, 2024
Int. Cl. B65D 55/06 (2006.01); A61J 1/14 (2023.01); A61J 1/18 (2023.01); B65D 39/00 (2006.01); B65D 45/16 (2006.01); B65D 51/00 (2006.01); B65D 51/18 (2006.01)
CPC B65D 55/066 (2013.01) [A61J 1/1412 (2013.01); A61J 1/18 (2013.01); B65D 39/0005 (2013.01); B65D 45/16 (2013.01); B65D 51/002 (2013.01); B65D 51/18 (2013.01); B65D 2251/0015 (2013.01); B65D 2251/0075 (2013.01); B65D 2401/55 (2020.05)] 19 Claims
OG exemplary drawing
 
1. A closure system for closing an opening of a container, comprising:
a stopper member made of an elastic material and having a plug portion configured to fit into the opening of the container and a cover portion configured to abut a boundary surface adjacent to the opening of the container;
a cage member configured to be mounted to the container;
a cover member reversibly mountable to the cage member; and
an integrity visualization member,
wherein the closure system is configured to be in an assembled state in which the plug portion of the stopper member is fitted into the opening of the container and the cage member is mounted to the container,
wherein the cage member is configured to apply a force to the cover portion of the stopper member to push the cover portion of the stopper member onto the boundary surface of the opening of the container when the closure system is in the assembled state,
wherein the cage member has an aperture to access the cover portion of the stopper member when the closure system is in the assembled state,
wherein the cover member covers the aperture of the cage member when being mounted to the cage member,
wherein the integrity visualization member is configured to indicate an integrity of the closure system and configured to be positioned between the cover member and the cage member when the closure system is in the assembled state,
wherein the closure system is configured such that integrity indicated by the integrity visualization member is recognizable, and
wherein the integrity visualization member is an integrity masking member configured to be adhered to the cage member such that the aperture of the cage member is covered.