US 12,478,748 B2
Aerosol delivery of at least two liquid compositions
Juergen Rawert, Cologne (DE); Frank Bartels, Hattingen (DE); and Steven Dudley, Brighton (GB)
Assigned to INVOX BELGIUM NV, Diepenbeek (BE)
Appl. No. 17/907,549
Filed by INVOX BELGIUM NV, Diepenbeek (BE)
PCT Filed Mar. 29, 2021, PCT No. PCT/EP2021/058109
§ 371(c)(1), (2) Date Sep. 28, 2022,
PCT Pub. No. WO2021/198154, PCT Pub. Date Oct. 7, 2021.
Claims priority of provisional application 63/002,836, filed on Mar. 31, 2020.
Claims priority of application No. 20167140 (EP), filed on Mar. 31, 2020.
Prior Publication US 2023/0218837 A1, Jul. 13, 2023
Int. Cl. A61M 15/00 (2006.01); A61K 31/357 (2006.01); A61K 31/407 (2006.01); A61K 31/538 (2006.01)
CPC A61M 15/0003 (2014.02) [A61K 31/357 (2013.01); A61K 31/407 (2013.01); A61K 31/538 (2013.01); A61M 15/0065 (2013.01); A61M 2205/8281 (2013.01)] 19 Claims
OG exemplary drawing
 
1. An inhalation device for the generation of an aerosol of at least two liquid compositions, the device comprising at least a first and second reservoir containing at least a first and a second liquid composition, wherein the inhalation device is a pump-actuated inhaler adapted to release upon actuation a metered dose of the first liquid composition from the first reservoir and a metered dose of the second liquid composition from the second reservoir, wherein the first and second reservoir for storing the first and second liquid composition are fluidically connected to at least a first and second pumping chamber for generation of a first pressure inside said first pumping chamber and a second pressure inside said second pumping chamber, a first and second riser pipe, each of which is able to be received with a reservoir-facing, interior end in said first and second pumping chamber, wherein the interior volume of the first and second pumping chamber is changeable by means of relative motion of the first and second pumping chamber to the first and second riser pipe, at least a first exit area and a second exit area adapted to separately eject the first and second liquid composition from the inhalation device, a first potential energy storage unit coupled with one end of the first pumping chamber, and a second potential energy storage unit coupled with one end of the second pumping chamber, wherein the first and the second potential energy storge units are configured to separately generate the first and the second pressures, respectively, for releasing the at least two liquid compositions.