US 12,478,727 B2
Compensation of pressure driven leakage while using high precision volumetric pumps
Fredrik Per Gunnar Oskarson, Brännö (SE); Anders Hans Lindström, Gothenburg (SE); and Karl Hannes Hultgren, Gothenburg (SE)
Assigned to Unfors RaySafe AB, Billdal (SE)
Filed by Unfors RaySafe AB, Billdal (SE)
Filed on Oct. 14, 2022, as Appl. No. 18/046,785.
Prior Publication US 2024/0123139 A1, Apr. 18, 2024
Int. Cl. A61M 5/142 (2006.01); A61M 5/145 (2006.01); A61M 5/168 (2006.01)
CPC A61M 5/14216 (2013.01) [A61M 5/1452 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method comprising:
calibrating a measurement apparatus comprising a pump wherein calibrating the measurement apparatus comprises creating a characterization of leakage through the pump as a function of a pressure difference over the pump;
operating the measurement apparatus for a predetermined time period to pump a liquid wherein operating the measurement apparatus comprises:
determining an amount of rotation a piston in the pump has made while the measurement apparatus operates for the predetermined time period, and
monitoring the pressure difference over the pump while the measurement apparatus operates for the predetermined time period;
determining a measurement of a flow through the measurement apparatus based on the amount of rotation of the piston; and
compensating the measurement of the flow for leakage of the pump while the measurement apparatus operated for the predetermined time period based on the characterization of leakage and the amount of rotation during the period and the monitored pressure difference over the pump.