US 12,478,652 B2
Bacteriophage therapy
Pascal Danglas, Saint-Prex (CH); and Laurent Debarbieux, Paris (FR)
Assigned to Ferring B.V., Hoofddorp (NL); and Institut Pasteur, Paris (FR)
Filed by FERRING B.V., Hoofddorp (NL); and INSTITUT PASTEUR, Paris (FR)
Filed on Jan. 30, 2024, as Appl. No. 18/427,221.
Application 18/427,221 is a division of application No. 17/353,337, filed on Jun. 21, 2021, granted, now 11,918,613.
Application 17/353,337 is a division of application No. 14/787,581, granted, now 11,040,078, previously published as PCT/EP2014/058840, filed on Apr. 30, 2014.
Claims priority of application No. 13305568 (EP), filed on Apr. 30, 2013.
Prior Publication US 2024/0342230 A1, Oct. 17, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 35/76 (2015.01); A61K 9/00 (2006.01); C12N 7/00 (2006.01)
CPC A61K 35/76 (2013.01) [A61K 9/0053 (2013.01); C12N 7/00 (2013.01); C12N 2795/10021 (2013.01); C12N 2795/10132 (2013.01); C12N 2795/10171 (2013.01); Y02A 50/30 (2018.01)] 14 Claims
 
1. A method of treating inflammatory bowel disease comprising administering to a subject in need thereof at least one bacteriophage strain capable of producing a lytic infection in an adherent-invasive Escherichia coli strain, thereby treating the subject, wherein the at least one bacteriophage strain is selected from:
the bacteriophage strain P1 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM I-4694;
the bacteriophage strain P2 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM I-4695;
the bacteriophage strain P3 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM I-4696;
the bacteriophage strain P4 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM I-4697;
the bacteriophage strain P5 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM I-4698;
the bacteriophage strain P6 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM I-4699; and
the bacteriophage strain P8 deposited with the French National Collection of Microorganisms at the Institut Pasteur under Accession Number CNCM I-4700.