US 12,478,634 B2
Compositions and methods for treating muscular dystrophy and other disorders
Qi Long Lu, Charlotte, NC (US); Marcela Cataldi, Harrisburg, NC (US); and Pei Juan Lu, Charlotte, NC (US)
Assigned to The Charlotte Mecklenburg Hospital Authority, Charlotte, NC (US)
Filed by The Charlotte Mecklenburg Hospital Authority, Charlotte, NC (US)
Filed on Feb. 12, 2024, as Appl. No. 18/438,820.
Application 18/438,820 is a continuation of application No. 17/222,662, filed on Apr. 5, 2021, granted, now 11,931,371.
Application 17/222,662 is a continuation of application No. 16/554,338, filed on Aug. 28, 2019, granted, now 10,993,954, issued on May 4, 2021.
Application 16/554,338 is a continuation of application No. 16/112,447, filed on Aug. 24, 2018, granted, now 10,434,113, issued on Oct. 8, 2019.
Application 16/112,447 is a continuation in part of application No. 15/842,580, filed on Dec. 14, 2017, granted, now 10,245,235, issued on Apr. 2, 2019.
Claims priority of provisional application 62/520,252, filed on Jun. 15, 2017.
Claims priority of provisional application 62/435,442, filed on Dec. 16, 2016.
Prior Publication US 2025/0009770 A1, Jan. 9, 2025
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/7004 (2006.01); A61K 31/047 (2006.01); A61P 21/00 (2006.01)
CPC A61K 31/7004 (2013.01) [A61K 31/047 (2013.01); A61P 21/00 (2018.01)] 10 Claims
 
1. A method of treating a Fukutin related protein (FKRP)-related muscular dystrophy, comprising administering to a human subject in need thereof a therapeutically effective amount of a compound of the following formula:

OG Complex Work Unit Chemistry
thereby treating the FKRP-related muscular dystrophy in the subject.